Luxury Expeditions to South America and the Galapagos Islands

Home to some of the might natural wonders and world extremes, South America is a prime expedition destination, filled with surprise and intrigue. Numerous cruise lines visit here on an expedition sailing, offering a luxury experience both on-board and ashore with included excursions, expert guides and enrichment activities.

From the mighty Amazon River to the unique world of the Galapagos Islands, this continent is a place that is truly one-of-a-kind. Explore the road less travelled with an expedition sailing that sails through the mystical Chilean Fjords or ventures to the lively cities of Brazil and Rio de Janeiro.

What to Expect on an Expedition Cruise to South America and the Galapagos Islands

South America sees four cruise lines visit the region on expedition cruises, some of which focus purely on visiting the Galapagos Islands, and others which explore the continent. Celebrity Cruises only visits the Galapagos Islands on expedition cruising, with three ships featured on itineraries. Silversea also has Silver Origin visiting the Galapagos, as well as Silver Wind, Silver Explorer and Silver Cloud sailing to the wider South America region. Both of Seabourn's ships, Venture and Pursuit, sailing to South America, alongside Scenic's flagship, Scenic Eclipse.

The only way to experience the Galapagos and South America is on-board luxury cruise ships that are specially designed to take you closer to the action than ever before. Small but perfectly formed, each of these ships reach some of the most remote corners of the region. But don’t think this means you need to compromise on comfort. Pairing intrepid exploration with pure, unadulterated luxury, the cruise lines which visit South America and the Galapagos Islands bring unforgettable excursions with fascinating on-board lectures, exquisite dining and plush all-suite accommodation. Every bar, lounge and deck offers panoramic views of the natural beauty sitting right outside your ship. Add talks from naturalists, peaceful libraries and indulgent hot tubs to your experience, and you will never forget your voyage of discovery.


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Magic of Colombia
Barranquilla | Nueva Venecia | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Calamar | Cartagena | Cartagena
30 Sep 2026
7 Nights
South America

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Magic of Colombia
Barranquilla | Nueva Venecia | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Calamar | Cartagena | Cartagena
03 Oct 2026
7 Nights
South America

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Was £4538pp
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REF: AMASA261003BC
7 Night Galapagos Outer Loop Cruise
Baltra Island, Galápagos | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Floreana Island, Galapagos | Punta Cormorant, Floreana Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Urbina Bay, Isabella Island, Galapagos | Vincente Roca Point, Isabella Island, Galapagos | Punta Espinoza, Fernandina Island, Galápagos | Daphne Major, Galapagos | South Plaza Island, Galápagos | Dragon Hill, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
04 Oct 2026
7 Nights
Pacific

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Was £6055pp
Now: £5522
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REF: CELEBFL07G058-041026
Ultimate America's Historic Journey to Panama
New York, New York | Wilmington, Delaware | Baltimore, Maryland | Yorktown, Virginia | Wilmington, North Carolina | Charleston, South Carolina | Miami, Florida | Key West, Florida | Nassau | Nassau | Staniel Cay | San Salvador Island | Cabo de la Vela | Cartagena | More...
05 Oct 2026
21 Nights
Panama Canal

Celebrate 5 years of Scenic Ocean with an ADDITIONAL 5% off ALL sailings - Call for your extra savings
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Wonders of Colombia
Cartagena | Palenque | Calamar | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Barranquilla | Nueva Venecia | Barranquilla
07 Oct 2026
7 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
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Was £4538pp
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REF: AMASB261007CB
Wonders of Colombia
Cartagena | Palenque | Calamar | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Barranquilla | Nueva Venecia | Barranquilla
10 Oct 2026
7 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
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Was £4538pp
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REF: AMASA261010CB
7 Night Galapagos Inner Loop Cruise
Baltra Island, Galápagos | Rabida Island | Puerto Egas | Elizabeth Bay, Isabela Island, Galápagos | Tagus Cove, Isabella Island, Galapagos | Bartolome Island | Sullivan Bay, Santiago Island, Galápagos | Daphne Major, Galapagos | North Seymour Island, Galapagos | Las Bachas, Santa Cruz Island, Galápagos | Punta Pitt, San Cristóbal Island, Galápagos | Puerto Baquerizo Moreno, San Cristobal Island, Galapagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
11 Oct 2026
7 Nights
Pacific

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Was £6241pp
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REF: CELEBFL07G057-111026
Magic of Colombia
Barranquilla | Nueva Venecia | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Calamar | Cartagena | Cartagena
14 Oct 2026
7 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
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Was £4538pp
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REF: AMASB261014BC
Pristine islands of the Bahamas & the Panama Canal
Nassau | Staniel Cay | San Salvador Island | Cabo de la Vela | Cartagena | San Blas Islands | Bocas del Toro | Panama City | Panama City
16 Oct 2026
10 Nights
Caribbean

Celebrate 5 years of Scenic Ocean with an ADDITIONAL 5% off ALL sailings - Call for your extra savings
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Was £7706pp
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Magic of Colombia
Barranquilla | Nueva Venecia | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Calamar | Cartagena | Cartagena
17 Oct 2026
7 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
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Was £4538pp
Now: £4356
pp
REF: AMASA261017BC
7 Night Galapagos Outer Loop Cruise
Baltra Island, Galápagos | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Floreana Island, Galapagos | Punta Cormorant, Floreana Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Urbina Bay, Isabella Island, Galapagos | Vincente Roca Point, Isabella Island, Galapagos | Punta Espinoza, Fernandina Island, Galápagos | Daphne Major, Galapagos | South Plaza Island, Galápagos | Dragon Hill, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
18 Oct 2026
7 Nights
Pacific

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
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Was £6561pp
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pp
REF: CELEBFL07G058-181026
Wonders of Colombia
Cartagena | Palenque | Calamar | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Barranquilla | Nueva Venecia | Barranquilla
21 Oct 2026
7 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
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Was £4538pp
Now: £4356
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REF: AMASB261021CB
Wonders of Colombia
Cartagena | Palenque | Calamar | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Barranquilla | Nueva Venecia | Barranquilla
24 Oct 2026
7 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
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Was £4538pp
Now: £4356
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REF: AMASA261024CB
7 Night Galapagos Inner Loop Cruise
Baltra Island, Galápagos | Rabida Island | Puerto Egas | Elizabeth Bay, Isabela Island, Galápagos | Tagus Cove, Isabella Island, Galapagos | Bartolome Island | Sullivan Bay, Santiago Island, Galápagos | Daphne Major, Galapagos | North Seymour Island, Galapagos | Las Bachas, Santa Cruz Island, Galápagos | Punta Pitt, San Cristóbal Island, Galápagos | Puerto Baquerizo Moreno, San Cristobal Island, Galapagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
25 Oct 2026
7 Nights
Pacific

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Was £6625pp
Now: £6042
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REF: CELEBFL07G057-251026
Wellness Retreat - Panama City to Valparaiso
Panama City | Valparaiso
26 Oct 2026
9 Nights
Panama Canal

Celebrate 5 years of Scenic Ocean with an ADDITIONAL 5% off ALL sailings - Call for your extra savings
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Magic of Colombia
Barranquilla | Nueva Venecia | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Calamar | Cartagena | Cartagena
28 Oct 2026
7 Nights
South America

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REF: AMASB261028BC
Epic Atlantic Escapade
Montréal, Québec | Quebec City, Québec | Saguenay, Québec | Sydney, Nova Scotia | Halifax, Nova Scotia | Santa Marta | Saint John's | Basseterre, Saint Kitts | Tortola | San Juan (Puerto Rico) | Miami, Florida
30 Oct 2026
16 Nights
Caribbean

Ultimate All-Inclusive Cruise Fare now includes: Round-trip Economy flights, transfers between airport and ship PLUS Private Executive Chauffeur Credit*
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
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Was £10344pp
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REF: REGENTSPL261030
Magic of Colombia
Barranquilla | Nueva Venecia | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Calamar | Cartagena | Cartagena
31 Oct 2026
7 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
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Was £4538pp
Now: £4356
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REF: AMASA261031BC
7 Night Galapagos Outer Loop Cruise
Baltra Island, Galápagos | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Floreana Island, Galapagos | Punta Cormorant, Floreana Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Urbina Bay, Isabella Island, Galapagos | Vincente Roca Point, Isabella Island, Galapagos | Punta Espinoza, Fernandina Island, Galápagos | Daphne Major, Galapagos | South Plaza Island, Galápagos | Dragon Hill, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
01 Nov 2026
7 Nights
Pacific

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
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Was £6429pp
Now: £5863
pp
REF: CELEBFL07G058-011126
Chilean Fjords & The Glaciers of The Beagle Channel
Valparaiso | Niebla | Puerto Montt | Castro | Puerto Edén | PIO X Glacier | Punta Arenas | Chilean Fjords | Chilean Fjords | Cape Horn | Buenos Aires | Ushuaia
04 Nov 2026
12 Nights
South America

Celebrate 5 years of Scenic Ocean with an ADDITIONAL 5% off ALL sailings - Call for your extra savings
Save up to 30%, return flights included and free private door to door transfers*
Complimentary helicopter flightseeing on 26/27 Antarctica Voyages
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
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Was £13304pp
Now: £12772
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Ultimate Chilean Fjords, Glaciers & Antarctic Wildlife Explorer
Valparaiso | Niebla | Puerto Montt | Castro | Puerto Edén | PIO X Glacier | Punta Arenas | Chilean Fjords | Chilean Fjords | Cape Horn | Ushuaia | Falkland Islands | Falkland Islands | South Georgia Island | More...
04 Nov 2026
30 Nights
Antarctica

Celebrate 5 years of Scenic Ocean with an ADDITIONAL 5% off ALL sailings - Call for your extra savings
Save up to 30%, return flights included and free private door to door transfers*
Complimentary helicopter flightseeing on 26/27 Antarctica Voyages
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
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Was £39390pp
Now: £37814
pp
REF: SCENIC202S041126-1
Wonders of Colombia
Cartagena | Palenque | Calamar | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Barranquilla | Nueva Venecia | Barranquilla
04 Nov 2026
7 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
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Was £4938pp
Now: £4740
pp
REF: AMASB261104CB
Wonders of Colombia
Cartagena | Palenque | Calamar | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Barranquilla | Nueva Venecia | Barranquilla
07 Nov 2026
7 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
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Was £4938pp
Now: £4740
pp
REF: AMASA261107CB
7 Night Galapagos Inner Loop Cruise
Baltra Island, Galápagos | Rabida Island | Puerto Egas | Elizabeth Bay, Isabela Island, Galápagos | Tagus Cove, Isabella Island, Galapagos | Bartolome Island | Sullivan Bay, Santiago Island, Galápagos | Daphne Major, Galapagos | North Seymour Island, Galapagos | Las Bachas, Santa Cruz Island, Galápagos | Punta Pitt, San Cristóbal Island, Galápagos | Puerto Baquerizo Moreno, San Cristobal Island, Galapagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
08 Nov 2026
7 Nights
Pacific

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
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Was £6817pp
Now: £6217
pp
REF: CELEBFL07G057-081126
Secrets Of The Amazon
Miami, Florida | Bridgetown | Port-of-Spain | Macapa | Santarém | Boca de Valeria | Manaus | Parintins | Alter do Chão | Macapa | Saint George's | San Juan (Puerto Rico) | Miami, Florida
09 Nov 2026
22 Nights
South America

Ultimate All-Inclusive Cruise Fare now includes: Round-trip Economy flights, transfers between airport and ship PLUS Private Executive Chauffeur Credit*
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £10534pp
Now: £9506
pp
REF: REGENTMAR261109

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