Panama Canal Luxury Cruises

Browse all available sailing dates for luxury cruise holidays to the Panama Canal. To find out more and to discover the best deals call us today and speak to our cruise experts. All Pnama Canal cruise holidays are fully ABTA & ATOL protected.

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Panama Canal Adventure
Miami, Florida | Georgetown, Grand Cayman | Cartagena | Puntarenas | Corinto | Puerto Quetzal | Acapulco | Cabo San Lucas | Ensenada | Los Angeles, California
08 Jan 2025
16 Nights
Oceania Vista
Panama Canal
Receive up to a four-category stateroom upgrade*!
FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Fly Cruise From
Was £7339pp
Now: £6972 pp
REF: OCEANIAVIS250108
Southampton to San Francisco
Southampton | New York, New York | New York, New York | Aruba | Puerto Quetzal | Cabo San Lucas | San Francisco, California | San Francisco, California
09 Jan 2025
26 Nights
Queen Anne
Transatlantic
FLASH SALE - 10% off 2025 voyages* - CALL us for your flash sale price!
Fly Cruise From
Was £8049pp
Now: £7888 pp
REF: CUNARDH504A
Fuerte Amador to Fort Lauderdale
Panama City | Cartagena | Cartagena | Oranjestad | Fort Lauderdale, Florida
11 Jan 2025
9 Nights
Silver Ray
South America
Save £2400 per couple
Cruise Only From
Was £4050pp
Now: £3847 pp
REF: SILVERRA250111S09
11 Night Panama Canal & S. Caribbean
Fort Lauderdale, Florida | Cartagena | Colón | Oranjestad | Willemstad | Kralendijk | Fort Lauderdale, Florida
13 Jan 2025
11 Nights
Celebrity Beyond
Panama Canal
Fly Cruise From
Was £2932pp
Now: £2166 pp
REF: CELEBBY11C019-130125
Panama Canal Adventure
Los Angeles, California | Ensenada | Cabo San Lucas | Acapulco | Puerto Quetzal | Corinto | Puntarenas | Cartagena | Georgetown, Grand Cayman | Miami, Florida
24 Jan 2025
16 Nights
Oceania Vista
Panama Canal
FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Fly Cruise From
Was £7639pp
Now: £6894 pp
REF: OCEANIAVIS250124
11 Night Canal & S. Caribbean
Fort Lauderdale, Florida | Cartagena | Colón | Oranjestad | Kralendijk | Willemstad | Fort Lauderdale, Florida
03 Feb 2025
11 Nights
Celebrity Beyond
Panama Canal
Fly Cruise From
Was £11350pp
Now: £10782 pp
REF: CELEBBY11C020-030225
Panama Canal Discovery
Miami, Florida | Cozumel | Costa Maya | Harvest Caye | Santo Tomás de Castilla | Roatán Island | Puerto Limón | Panama City | Panama City | Panama City | Cartagena | Santa Marta | Oranjestad | Willemstad | More...
08 Feb 2025
21 Nights
Oceania Sirena
Panama Canal
FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Fly Cruise From
Was £6829pp
Now: £6163 pp
REF: OCEANIASIR250208A
Panama Potpourri
Miami, Florida | Cozumel | Costa Maya | Harvest Caye | Santo Tomás de Castilla | Roatán Island | Puerto Limón | Panama City | Panama City
08 Feb 2025
10 Nights
Oceania Sirena
Panama Canal
FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Fly Cruise From
Was £4459pp
Now: £4024 pp
REF: OCEANIASIR250208
Classic Panama Canal
Panama City | Panama City | Cartagena | Santa Marta | Oranjestad | Willemstad | Kralendijk | Port Antonio | Nassau | Miami, Florida
18 Feb 2025
11 Nights
Oceania Sirena
Panama Canal
FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Fly Cruise From
Was £4749pp
Now: £4285 pp
REF: OCEANIASIR250218
11 Night Panama Canal & S. Caribbean
Fort Lauderdale, Florida | Cartagena | Colón | Oranjestad | Willemstad | Kralendijk | Fort Lauderdale, Florida
24 Feb 2025
11 Nights
Celebrity Beyond
Panama Canal
Fly Cruise From
Was £7296pp
Now: £6931 pp
REF: CELEBBY11C019-240225
11 Night Canal & S. Caribbean
Fort Lauderdale, Florida | Cartagena | Colón | Kralendijk | Oranjestad | Georgetown, Grand Cayman | Fort Lauderdale, Florida
17 Mar 2025
11 Nights
Celebrity Beyond
Panama Canal
Fly Cruise From
Was £6426pp
Now: £6104 pp
REF: CELEBBY11C021-170325
Pearls Of The Panama Canal
Miami, Florida | Cozumel | Costa Maya | Santo Tomás de Castilla | Harvest Caye | Roatán Island | Puerto Limón | Panama City | Panama City | Panama City | Cartagena | Santa Marta | Oranjestad | Willemstad | More...
23 Mar 2025
20 Nights
Oceania Sirena
Panama Canal
FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Fly Cruise From
Was £6529pp
Now: £5892 pp
REF: OCEANIASIR250323A
Panama Potpourri
Miami, Florida | Cozumel | Costa Maya | Santo Tomás de Castilla | Harvest Caye | Roatán Island | Puerto Limón | Panama City | Panama City
23 Mar 2025
10 Nights
Oceania Sirena
Panama Canal
Receive up to a four-category stateroom upgrade*!
FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Fly Cruise From
Was £4299pp
Now: £3267 pp
REF: OCEANIASIR250323
Captivating Panama Canal
Panama City | Panama City | Cartagena | Santa Marta | Oranjestad | Willemstad | Kralendijk | Port Antonio | Miami, Florida
02 Apr 2025
10 Nights
Oceania Sirena
Panama Canal
FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Fly Cruise From
Was £4449pp
Now: £4015 pp
REF: OCEANIASIR250402
11 Night Panama Canal & S. Caribbean
Fort Lauderdale, Florida | Cartagena | Colón | Oranjestad | Willemstad | Kralendijk | Fort Lauderdale, Florida
07 Apr 2025
11 Nights
Celebrity Beyond
Panama Canal
Fly Cruise From
Was £4769pp
Now: £4530 pp
REF: CELEBBY11C019-070425
19-Day Panama Canal Passage
Long Beach, California | Puerto Vallarta | Huatulco (Santa María Huatulco) | Puerto Chiapas | Puerto Quetzal | Puntarenas | Cartagena | Miami, Florida
09 Apr 2025
19 Nights
Seabourn Encore
Panama Canal
Receive up to $2,200 to spend on-board per couple! - ENDS 3rd September
Cruise Only From
Was £7019pp
Now: £6201 pp
REF: SBN7521
31-Day Panama Canal & Atlantic Ocean Passage
Long Beach, California | Puerto Vallarta | Huatulco (Santa María Huatulco) | Puerto Chiapas | Puerto Quetzal | Puntarenas | Cartagena | Miami, Florida | Ponta Delgada, Azores | Lisbon
09 Apr 2025
31 Nights
Seabourn Encore
Panama Canal
Receive up to $2,200 to spend on-board per couple! - ENDS 3rd September
Cruise Only From
Was £8909pp
Now: £7871 pp
REF: SBN7521A
Panama Canal Crossing - San Diego to Fort Lauderdale
San Diego, California | San Diego, California | Cabo San Lucas | Puntarenas | Panama City | Cartagena | Fort Lauderdale, Florida
09 May 2025
18 Nights
Silver Shadow
Caribbean
Limited time 10% savings included
Save £2400 per couple
Fly Cruise From
Was £9100pp
Now: £6308 pp
REF: SILVERSS250509018
San Diego to Fuerte Amador
San Diego, California | San Diego, California | Cabo San Lucas | Puntarenas | Panama City
09 May 2025
11 Nights
Silver Shadow
Caribbean
Save £2400 per couple
Cruise Only From
Was £5150pp
Now: £4647 pp
REF: SILVERSS250509S11
Los Angeles, California to New York, NY
San Diego, California | San Diego, California | Cabo San Lucas | Puntarenas | Panama City | Cartagena | Fort Lauderdale, Florida | Fort Lauderdale, Florida | Samaná | Oranjestad | Gustavia | Saint Thomas | Hamilton | Hamilton | More...
09 May 2025
33 Nights
Silver Shadow
Caribbean
Save £2400 per couple
Fly Cruise From
Was £10300pp
Now: £9295 pp
REF: SILVERSS250509C33
Fuerte Amador to Fort Lauderdale
Panama City | Cartagena | Fort Lauderdale, Florida
20 May 2025
7 Nights
Silver Shadow
Caribbean
Save £2400 per couple
Cruise Only From
Was £4450pp
Now: £4016 pp
REF: SILVERSS250520S07
West Coast Wonders
San Francisco, California | Los Angeles, California | Ensenada | Cabo San Lucas | Acapulco | Puerto Quetzal | Corinto | Puntarenas | Cartagena | Georgetown, Grand Cayman | Miami, Florida
06 Jun 2025
18 Nights
Seven Seas Mariner
Panama Canal
Ultimate All-Inclusive Cruise Fare now includes: Round-trip Economy flights, transfers between airport and ship PLUS Private Executive Chauffeur Credit*
Fly Cruise From
Was £12329pp
Now: £11126 pp
REF: REGENTMAR250606
Panoramic Panama Canal
San Diego, California | Cabo San Lucas | Zihuatanejo | Puerto Quetzal | Corinto | Puntarenas | Cartagena | Georgetown, Grand Cayman | Miami, Florida | Port Canaveral, Florida | New York, New York | New York, New York
03 Jul 2025
20 Nights
Oceania Insignia
Panama Canal
Exotic sale event - Save up to 55%*
FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Fly Cruise From
Was £6459pp
Now: £4099 pp
REF: OCEANIAINS250703
Seattle to Miami
Seattle, Washington | Ketchikan, Alaska | Juneau, Alaska | Tracy Arm, Alaska | Sitka, Alaska | Victoria, British Columbia | Seattle, Washington | San Francisco, California | Los Angeles, California | Cabo San Lucas | Puntarenas | Cartagena | Aruba | Miami, Florida More...
18 Sep 2025
28 Nights
Queen Elizabeth
Transatlantic
FLASH SALE - 10% off 2025 voyages* - CALL us for your flash sale price!
Fly Cruise From
Was £8129pp
Now: £7966 pp
REF: CUNARDQ527B
Seattle to Miami
Seattle, Washington | Ketchikan, Alaska | Juneau, Alaska | Tracy Arm, Alaska | Sitka, Alaska | Victoria, British Columbia | Seattle, Washington | San Francisco, California | Los Angeles, California | Cabo San Lucas | Puntarenas | Cartagena | Aruba | Miami, Florida | More...
18 Sep 2025
40 Nights
Queen Elizabeth
Transatlantic
FLASH SALE - 10% off 2025 voyages* - CALL us for your flash sale price!
Fly Cruise From
Was £10329pp
Now: £10122 pp
REF: CUNARDQ527C

Prices are subject to change and availability. Prices may vary depending on airport selected. Promotions are only applicable to select cabins grades, please call for details

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