Luxury South America Cruises

Luxury cruises in South America are all about the experience. Book one of the cruise deals below and you will have the opportunity to trek through wildlife-rich jungles, marvel at thundering waterfalls, visit ancient Incan ruins, and much more. Depending on the type of cruise you book, you may also get the chance to experience something truly unique, exclusively packaged up with luxury hotel stays and one-of-a-kind tours.

Find Out More About Cruising in South America


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Verdant Atlantic Vistas
Buenos Aires | Buenos Aires | Montevideo | Punta del Este | Balneário de Camboriú | São Francisco do Sul | Santos | Parati | Ilha Grande | Buzios | Rio de Janeiro | Rio de Janeiro | Buzios | Salvador de Bahia | More...
24 Mar 2025
38 Nights
Atlantic Islands

FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Ends 30th September - Last chance to book and receive a FREE house select beverage package
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £12149pp
Now: £11541
pp
REF: OCEANIAMNA250324B
Brilliant Brazil & Iberia
Buenos Aires | Buenos Aires | Montevideo | Punta del Este | Balneário de Camboriú | São Francisco do Sul | Santos | Parati | Ilha Grande | Buzios | Rio de Janeiro | Rio de Janeiro | Buzios | Salvador de Bahia | More...
24 Mar 2025
45 Nights
World-wide

FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Ends 30th September - Last chance to book and receive a FREE house select beverage package
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £14489pp
Now: £13076
pp
REF: OCEANIAMNA250324C
Wild Antarctica featuring the Weddell Sea
Punta Arenas | Punta Arenas | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Ushuaia
24 Mar 2025
11 Nights
Antarctica

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £8882pp
Now: £8615
pp
REF: AURORAANW009S
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | El Barranco, Genovesa Island, Galápagos | Darwin Bay, Genovesa Island, Galápagos | Sullivan Bay, Santiago Island, Galápagos | North Seymour Island, Galapagos | Punta Moreno, Isabella Island, Galapagos | Mangle Point, Fernandina Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Cerro Brujo, San Cristóbal Island, Galápagos | San Cristóbal Island, Galápagos | More...
29 Mar 2025
7 Nights
Pacific

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £29500pp
Now: £11552
pp
REF: SILVEROR250329007
7 Night Galapagos Inner Loop Cruise
Baltra Island, Galápagos | Rabida Island | Puerto Egas | Elizabeth Bay, Isabela Island, Galápagos | Tagus Cove, Isabella Island, Galapagos | Bartolome Island | Sullivan Bay, Santiago Island, Galápagos | Daphne Major, Galapagos | North Seymour Island, Galapagos | Las Bachas, Santa Cruz Island, Galápagos | Punta Pitt, San Cristóbal Island, Galápagos | Puerto Baquerizo Moreno, San Cristobal Island, Galapagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
30 Mar 2025
7 Nights
Pacific

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £13649pp
Now: £8559
pp
REF: CELEBFL07G055-300325
Remote Wonders of the Pacific and Easter Island's Legends - Valparaiso to Papeete
Valparaiso | San Juan Bautista (Robinson Crusoe Island) | Alejandro Selkirk Island | Hangaroa, Easter Island | Hangaroa, Easter Island | Pitcairn Island | Pitcairn Island | Nuku Hiva Island | Atuona, Hiva Oa | Tahuata Island | Hana Vave, Fatu Hiva Island | Rangiroa | Papeete, Tahiti
31 Mar 2025
23 Nights
Pacific

Limited time 10% savings included
Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £11100pp
Now: £7933
pp
REF: SILVERE4250331023
Valparaiso to Lautoka
Valparaiso | San Juan Bautista (Robinson Crusoe Island) | Alejandro Selkirk Island | Hangaroa, Easter Island | Hangaroa, Easter Island | Pitcairn Island | Pitcairn Island | Nuku Hiva Island | Atuona, Hiva Oa | Tahuata Island | Hana Vave, Fatu Hiva Island | Rangiroa | Papeete, Tahiti | Papeete, Tahiti | More...
31 Mar 2025
50 Nights
Pacific

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £40400pp
Now: £36461
pp
REF: SILVERE4250331C49
Fort Lauderdale to Los Angeles
Fort Lauderdale, Florida | Cartagena | Cartagena | Puntarenas | Puerto Quetzal | Puerto Vallarta | Cabo San Lucas | Los Angeles, California
01 Apr 2025
18 Nights
Caribbean

$200 FREE to spend on-board - ONLY when booking with SixStarCruises
Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £8800pp
Now: £6769
pp
REF: SILVERMO250401018
Captivating Panama Canal
Panama City | Panama City | Cartagena | Santa Marta | Oranjestad | Willemstad | Kralendijk | Port Antonio | Miami, Florida
02 Apr 2025
10 Nights
Panama Canal

FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Ends 30th September - Last chance to book and receive a FREE house select beverage package
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £4449pp
Now: £4015
pp
REF: OCEANIASIR250402
A Grand Journey Bridging America, Azore Isles and Catalonia
Miami, Florida | Kings Wharf | Horta, Azores | Azores | Lisbon | Cartagena | Valencia | Barcelona
02 Apr 2025
16 Nights
Mediterranean

Sail Unique - Value savings included PLUS book with a low 10% deposit*
Penthouse Dream - Reserve an Ocean Penthouse and receive a complimentary one-category upgrade
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £5040pp
Now: £4788
pp
REF: EXPLORAEX20250402MIABCN
An Extended Journey Bridging America and the Med’s Ancient Greats
Miami, Florida | Kings Wharf | Horta, Azores | Azores | Lisbon | Cartagena | Valencia | Barcelona | Palma de Mallorca | Palermo | Valletta | Khania | Rhodes | Kusadasi | More...
02 Apr 2025
26 Nights
Mediterranean

Sail Unique - Value savings included PLUS book with a low 10% deposit*
Penthouse Dream - Reserve an Ocean Penthouse and receive a complimentary one-category upgrade
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £9150pp
Now: £8692
pp
REF: EXPLORAEX20250402MIAPIR
Crossing the Equator: Rio to the Spanish Riviera
Rio de Janeiro | Buzios | Salvador de Bahia | Fernando de Noronha | Praia, Santiago Island | Porto Novo, Santo Antão Island | Santa Cruz de Tenerife | Tangier | Gibraltar | Málaga
03 Apr 2025
19 Nights
Transatlantic

Celebrate 5 years of Scenic Ocean with an ADDITIONAL 5% off ALL sailings - Call for your extra savings
Save up to 30%, return flights included and free private door to door transfers*
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £14645pp
Now: £14059
pp
REF: SCENIC401R030425-1
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | Bartolome Island | Santiago Island, Galápagos | Punta Vicente Roca, Isabela Island, Galápagos | Punta Espinoza, Fernandina Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Caleta Tagus | Champion Island, Galápagos | Post Office Bay, Floreana, Galápagos | Punta Cormorant, Floreana Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Santa Cruz Island, Galápagos | More...
05 Apr 2025
7 Nights
Pacific

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £12600pp
Now: £11371
pp
REF: SILVEROR250405007
Icons Of Brazil & Iberia
Rio de Janeiro | Buzios | Salvador de Bahia | Maceió | Recife | Mindelo, São Vicente Island | Dakar | San Sebastian de la Gomera | Santa Cruz de Tenerife | Santa Cruz de La Palma | Funchal, Madeira | Casablanca | Gibraltar | Almería | More...
05 Apr 2025
26 Nights
Transatlantic

FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Ends 30th September - Last chance to book and receive a FREE house select beverage package
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £6799pp
Now: £6459
pp
REF: OCEANIAMNA250405A
Samba & Flamenco Rhythms
Rio de Janeiro | Buzios | Salvador de Bahia | Maceió | Recife | Mindelo, São Vicente Island | Dakar | San Sebastian de la Gomera | Santa Cruz de Tenerife | Santa Cruz de La Palma | Funchal, Madeira | Casablanca | Gibraltar | Almería | More...
05 Apr 2025
33 Nights
Transatlantic

FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Ends 30th September - Last chance to book and receive a FREE house select beverage package
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £8429pp
Now: £7607
pp
REF: OCEANIAMNA250405B
Sumptuous South Atlantic
Rio de Janeiro | Buzios | Salvador de Bahia | Maceió | Recife | Mindelo, São Vicente Island | Dakar | San Sebastian de la Gomera | Santa Cruz de Tenerife
05 Apr 2025
16 Nights
Atlantic Islands

Receive up to a four-category stateroom upgrade*!
FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Ends 30th September - Last chance to book and receive a FREE house select beverage package
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £3665pp
Now: £3308
pp
REF: OCEANIAMNA250405
11 Night Panama Canal & S. Caribbean
Fort Lauderdale, Florida | Cartagena | Colón | Oranjestad | Willemstad | Kralendijk | Fort Lauderdale, Florida
07 Apr 2025
11 Nights
Panama Canal

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £4851pp
Now: £4608
pp
REF: CELEBBY11C019-070425
19-Day Panama Canal Passage
Long Beach, California | Puerto Vallarta | Huatulco (Santa María Huatulco) | Puerto Chiapas | Puerto Quetzal | Puntarenas | Cartagena | Miami, Florida
09 Apr 2025
19 Nights
Panama Canal

EXCLUSIVE $600 to spend on-board* - must end 23rd September
Sail into Savings - Save up to 15% on selected Ocean and Expedition Voyages
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £7019pp
Now: £6201
pp
REF: SBN7521
31-Day Panama Canal & Atlantic Ocean Passage
Long Beach, California | Puerto Vallarta | Huatulco (Santa María Huatulco) | Puerto Chiapas | Puerto Quetzal | Puntarenas | Cartagena | Miami, Florida | Ponta Delgada, Azores | Lisbon
09 Apr 2025
31 Nights
Panama Canal

EXCLUSIVE $600 to spend on-board* - must end 23rd September
Sail into Savings - Save up to 15% on selected Ocean and Expedition Voyages
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £8909pp
Now: £7871
pp
REF: SBN7521A
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | El Barranco, Genovesa Island, Galápagos | Darwin Bay, Genovesa Island, Galápagos | Sullivan Bay, Santiago Island, Galápagos | North Seymour Island, Galapagos | Punta Moreno, Isabella Island, Galapagos | Mangle Point, Fernandina Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Cerro Brujo, San Cristóbal Island, Galápagos | San Cristóbal Island, Galápagos | More...
12 Apr 2025
7 Nights
Pacific

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £12500pp
Now: £11875
pp
REF: SILVEROR250412007
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | Bartolome Island | Santiago Island, Galápagos | Punta Vicente Roca, Isabela Island, Galápagos | Punta Espinoza, Fernandina Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Caleta Tagus | Champion Island, Galápagos | Post Office Bay, Floreana, Galápagos | Punta Cormorant, Floreana Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Santa Cruz Island, Galápagos | More...
19 Apr 2025
7 Nights
Pacific

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £11800pp
Now: £10649
pp
REF: SILVEROR250419007
7 Night Galapagos Outer Loop Cruise
Baltra Island, Galápagos | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Floreana Island, Galapagos | Punta Cormorant, Floreana Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Urbina Bay, Isabella Island, Galapagos | Vincente Roca Point, Isabella Island, Galapagos | Punta Espinoza, Fernandina Island, Galápagos | Daphne Major, Galapagos | South Plaza Island, Galápagos | Dragon Hill, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
20 Apr 2025
7 Nights
Pacific

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £11553pp
Now: £8683
pp
REF: CELEBFL07G056-200425
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | El Barranco, Genovesa Island, Galápagos | Darwin Bay, Genovesa Island, Galápagos | Sullivan Bay, Santiago Island, Galápagos | North Seymour Island, Galapagos | Punta Moreno, Isabella Island, Galapagos | Mangle Point, Fernandina Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Cerro Brujo, San Cristóbal Island, Galápagos | San Cristóbal Island, Galápagos | More...
26 Apr 2025
7 Nights
Pacific

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £13900pp
Now: £12544
pp
REF: SILVEROR250426007
Magic of Colombia
Barranquilla | Nueva Venecia | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Calamar | Cartagena | Cartagena
03 May 2025
7 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £5715pp
Now: £5486
pp
REF: AMASA250503BC
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | Bartolome Island | Santiago Island, Galápagos | Punta Vicente Roca, Isabela Island, Galápagos | Punta Espinoza, Fernandina Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Caleta Tagus | Champion Island, Galápagos | Post Office Bay, Floreana, Galápagos | Punta Cormorant, Floreana Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Santa Cruz Island, Galápagos | More...
03 May 2025
7 Nights
Pacific

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £13500pp
Now: £12183
pp
REF: SILVEROR250503007

Explore South America on a Finest Collection voyage

Our Finest Collection cruise packages in South America offer tailor-made adventures exclusively for you. Your cruise is paired with a set of immersive land tours dedicated to helping you get right to the heart of the ports on your itinerary. What's more, after days spent hiking across glaciers or exploring iconic cities accompanied by a local tour guide, you can retire to a five-star hotel for a gourmet dinner and spot of well-earned relaxation. 

South America expedition cruises

If you want your South America cruise adventure to be even more unforgettable, embark on an expedition cruise and feel like a true explorer. Sailing to destinations like mysterious Easter Island, wild and rugged Chile, and the positively prehistoric Galapagos islands; once-in-a-lifetime experiences are guaranteed. Accompanied by a dedicated group of expedition experts - from marine biologists to professional adventurers - you willl live like an intrepid explorer and witness natural wonders most people can only dream of.

Book South America cruises with our Cruise Concierge team

If you would like to embark on an adventure you will never forget, call our Cruise Concierge team to book one of the itineraries below. And if you can't find exactly what you are looking for? Call us to build a completely bespoke cruise in South America that incorporates every port and experience you have been dreaming of.

Our Award Winning Service


Best Workplaces in Travel 2024
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TTG Luxury Cruise Agency Of The Year
TTG Luxury Cruise Agency Of The Year
Best Use Of Content 2023
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Best Specialist Cruise Agent 2023
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UK Cruise Awards Winners 2023
UK Cruise Awards Winners 2023
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Travel Weekly Large Cruise Agency of the Year 2023
Travel Weekly Large Cruise Agency of the Year 2023