Luxury South America Cruises

Luxury cruises in South America are all about the experience. Book one of the cruise deals below and you will have the opportunity to trek through wildlife-rich jungles, marvel at thundering waterfalls, visit ancient Incan ruins, and much more. Depending on the type of cruise you book, you may also get the chance to experience something truly unique, exclusively packaged up with luxury hotel stays and one-of-a-kind tours.

Find Out More About Cruising in South America


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Glaciers & Lighthouses
Reykjavík | Djúpivogur | Husavik | Isafjørdur | Qaqortoq (Julianehaab) | Paamiut (Fredrikshaab) | Nuuk (Godthaab) | Santos | Corner Brook, Newfoundland and Labrador | Saint-John, New Brunswick | Bar Harbor, Maine | Boston, Massachusetts | Martha's Vineyard, Massachusetts | New York, New York More...
25 Aug 2025
19 Nights
Northern Europe

FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Ends 30th September - Last chance to book and receive a FREE house select beverage package
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £6669pp
Now: £6018
pp
REF: OCEANIAINS250825
Wonders of Colombia
Cartagena | Palenque | Calamar | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Barranquilla | Nueva Venecia | Barranquilla
27 Aug 2025
7 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £4900pp
Now: £4704
pp
REF: AMASB250827CB
Wonders of Colombia
Cartagena | Palenque | Calamar | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Barranquilla | Nueva Venecia | Barranquilla
30 Aug 2025
7 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £4839pp
Now: £4645
pp
REF: AMASA250830CB
7 Night Galapagos Inner Loop Cruise
Baltra Island, Galápagos | Rabida Island | Puerto Egas | Elizabeth Bay, Isabela Island, Galápagos | Tagus Cove, Isabella Island, Galapagos | Bartolome Island | Sullivan Bay, Santiago Island, Galápagos | Daphne Major, Galapagos | North Seymour Island, Galapagos | Las Bachas, Santa Cruz Island, Galápagos | Punta Pitt, San Cristóbal Island, Galápagos | Puerto Baquerizo Moreno, San Cristobal Island, Galapagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
31 Aug 2025
7 Nights
Pacific

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £7313pp
Now: £6669
pp
REF: CELEBFL07G055-310825
Magic of Colombia
Barranquilla | Nueva Venecia | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Calamar | Cartagena | Cartagena
03 Sep 2025
7 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £4504pp
Now: £4324
pp
REF: AMASB250903BC
75-Day New Guinea's Islands To Patagonia & Antarctica
Darwin, Northern Territory | Agats | Kokas | Misool, Raja Ampat | Yenwaoupnor | Mansuar Island | Manokwari, Irian Jaya | Cenderawasih Bay | Cenderawasih Bay | Jayapura, Irian Jaya | Vanimo | Garove Island | Rabaul, Bismarck Archipelago | Duke of York Island | More...
04 Sep 2025
75 Nights
Antarctica

EXCLUSIVE $600 to spend on-board* - must end 23rd September
Sail into Savings - Save up to 15% on selected Ocean and Expedition Voyages
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £44278pp
Now: £39124
pp
REF: SBNP546C
Magic of Colombia
Barranquilla | Nueva Venecia | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Calamar | Cartagena | Cartagena
06 Sep 2025
7 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £4565pp
Now: £4382
pp
REF: AMASA250906BC
7 Night Galapagos Outer Loop Cruise
Baltra Island, Galápagos | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Floreana Island, Galapagos | Punta Cormorant, Floreana Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Urbina Bay, Isabella Island, Galapagos | Vincente Roca Point, Isabella Island, Galapagos | Punta Espinoza, Fernandina Island, Galápagos | Daphne Major, Galapagos | South Plaza Island, Galápagos | Dragon Hill, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
07 Sep 2025
7 Nights
Pacific

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £7686pp
Now: £6801
pp
REF: CELEBFL07G056-070925
Wonders of Colombia
Cartagena | Palenque | Calamar | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Barranquilla | Nueva Venecia | Barranquilla
10 Sep 2025
7 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £4565pp
Now: £4382
pp
REF: AMASB250910CB
Peruvian Amazon & Machu Picchu Exploration
Lima | Lima | Iquitos | Nauta | Nauta | Urubamba | Cusco | Cusco | Cusco | Lima | Lima
10 Sep 2025
15 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £13099pp
Now: £12575
pp
REF: UNIWORLD50623
Peruvian Rivers & Rainforest Discovery
Lima | Lima | Iquitos | Nauta | Nauta | Lima
10 Sep 2025
10 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £11899pp
Now: £11423
pp
REF: UNIWORLD50634
Wonders of Colombia
Cartagena | Palenque | Calamar | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Barranquilla | Nueva Venecia | Barranquilla
13 Sep 2025
7 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £5398pp
Now: £5182
pp
REF: AMASA250913CB
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | El Barranco, Genovesa Island, Galápagos | Darwin Bay, Genovesa Island, Galápagos | Sullivan Bay, Santiago Island, Galápagos | North Seymour Island, Galapagos | Punta Moreno, Isabella Island, Galapagos | Mangle Point, Fernandina Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Cerro Brujo, San Cristóbal Island, Galápagos | San Cristóbal Island, Galápagos | More...
13 Sep 2025
7 Nights
Pacific

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £10600pp
Now: £9566
pp
REF: SILVEROR250913007
7 Night Galapagos Inner Loop Cruise
Baltra Island, Galápagos | Rabida Island | Puerto Egas | Elizabeth Bay, Isabela Island, Galápagos | Tagus Cove, Isabella Island, Galapagos | Bartolome Island | Sullivan Bay, Santiago Island, Galápagos | Daphne Major, Galapagos | North Seymour Island, Galapagos | Las Bachas, Santa Cruz Island, Galápagos | Punta Pitt, San Cristóbal Island, Galápagos | Puerto Baquerizo Moreno, San Cristobal Island, Galapagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
14 Sep 2025
7 Nights
Pacific

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £8057pp
Now: £7348
pp
REF: CELEBFL07G055-140925
Magic of Colombia
Barranquilla | Nueva Venecia | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Calamar | Cartagena | Cartagena
17 Sep 2025
7 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £5726pp
Now: £5305
pp
REF: AMASB250917BC
Seattle to Miami
Seattle, Washington | Ketchikan, Alaska | Juneau, Alaska | Tracy Arm, Alaska | Sitka, Alaska | Victoria, British Columbia | Seattle, Washington | San Francisco, California | Los Angeles, California | Cabo San Lucas | Puntarenas | Cartagena | Aruba | Miami, Florida More...
18 Sep 2025
28 Nights
Transatlantic

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £8129pp
Now: £7966
pp
REF: CUNARDQ527B
Seattle to Miami
Seattle, Washington | Ketchikan, Alaska | Juneau, Alaska | Tracy Arm, Alaska | Sitka, Alaska | Victoria, British Columbia | Seattle, Washington | San Francisco, California | Los Angeles, California | Cabo San Lucas | Puntarenas | Cartagena | Aruba | Miami, Florida | More...
18 Sep 2025
40 Nights
Transatlantic

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £10329pp
Now: £10122
pp
REF: CUNARDQ527C
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | Bartolome Island | Santiago Island, Galápagos | Punta Vicente Roca, Isabela Island, Galápagos | Punta Espinoza, Fernandina Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Caleta Tagus | Champion Island, Galápagos | Post Office Bay, Floreana, Galápagos | Punta Cormorant, Floreana Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Santa Cruz Island, Galápagos | More...
20 Sep 2025
7 Nights
Pacific

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £11200pp
Now: £10108
pp
REF: SILVEROR250920007
7 Night Galapagos Outer Loop Cruise
Baltra Island, Galápagos | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Floreana Island, Galapagos | Punta Cormorant, Floreana Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Urbina Bay, Isabella Island, Galapagos | Vincente Roca Point, Isabella Island, Galapagos | Punta Espinoza, Fernandina Island, Galápagos | Daphne Major, Galapagos | South Plaza Island, Galápagos | Dragon Hill, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
21 Sep 2025
7 Nights
Pacific

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £7881pp
Now: £6560
pp
REF: CELEBFL07G056-210925
Crossing the Equator: Portugal to Brazil
Lisbon | Funchal, Madeira | Santa Cruz de Tenerife | Sao Vicente Island | Recife | Salvador de Bahia | Abrolhos Archipelago | Rio de Janeiro
24 Sep 2025
17 Nights
Transatlantic

Celebrate 5 years of Scenic Ocean with an ADDITIONAL 5% off ALL sailings - Call for your extra savings
Save up to 30%, return flights included and free private door to door transfers*
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £8818pp
Now: £8465
pp
REF: SCENIC101R240925-2
Wonders of Colombia
Cartagena | Palenque | Calamar | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Barranquilla | Nueva Venecia | Barranquilla
24 Sep 2025
7 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £4492pp
Now: £4312
pp
REF: AMASB250924CB
Seattle to Miami
Seattle, Washington | San Francisco, California | Los Angeles, California | Cabo San Lucas | Puntarenas | Cartagena | Aruba | Miami, Florida
25 Sep 2025
21 Nights
Transatlantic

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £4999pp
Now: £4899
pp
REF: CUNARDQ528
Seattle to Miami
Seattle, Washington | San Francisco, California | Los Angeles, California | Cabo San Lucas | Puntarenas | Cartagena | Aruba | Miami, Florida | San Juan (Puerto Rico) | Saint John's | Castries | Bridgetown | Sint Maarten | Tortola | More...
25 Sep 2025
33 Nights
Transatlantic

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £8659pp
Now: £8485
pp
REF: CUNARDQ528B
34-Day Across Oceanic Cultures: Fiji To The Chilean Coast
Lautoka | Kadavu Island | Fulaga Island | Pangai | Nukupule | Vava'u | Apia | Alofi | Aitutaki | Raiatea | Huahine | Papeete, Tahiti | Anaa | Fakarava | More...
27 Sep 2025
34 Nights
Pacific

EXCLUSIVE $600 to spend on-board* - must end 23rd September
Sail into Savings - Save up to 15% on selected Ocean and Expedition Voyages
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £20699pp
Now: £18289
pp
REF: SBNP549A
52-Day Fiji To The Chilean Coast & Antarctica
Lautoka | Kadavu Island | Fulaga Island | Pangai | Nukupule | Vava'u | Apia | Alofi | Aitutaki | Raiatea | Huahine | Papeete, Tahiti | Anaa | Fakarava | More...
27 Sep 2025
52 Nights
Antarctica

EXCLUSIVE $600 to spend on-board* - must end 23rd September
Sail into Savings - Save up to 15% on selected Ocean and Expedition Voyages
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £32038pp
Now: £28308
pp
REF: SBNP549B

Explore South America on a Finest Collection voyage

Our Finest Collection cruise packages in South America offer tailor-made adventures exclusively for you. Your cruise is paired with a set of immersive land tours dedicated to helping you get right to the heart of the ports on your itinerary. What's more, after days spent hiking across glaciers or exploring iconic cities accompanied by a local tour guide, you can retire to a five-star hotel for a gourmet dinner and spot of well-earned relaxation. 

South America expedition cruises

If you want your South America cruise adventure to be even more unforgettable, embark on an expedition cruise and feel like a true explorer. Sailing to destinations like mysterious Easter Island, wild and rugged Chile, and the positively prehistoric Galapagos islands; once-in-a-lifetime experiences are guaranteed. Accompanied by a dedicated group of expedition experts - from marine biologists to professional adventurers - you willl live like an intrepid explorer and witness natural wonders most people can only dream of.

Book South America cruises with our Cruise Concierge team

If you would like to embark on an adventure you will never forget, call our Cruise Concierge team to book one of the itineraries below. And if you can't find exactly what you are looking for? Call us to build a completely bespoke cruise in South America that incorporates every port and experience you have been dreaming of.

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