Luxury South America Cruises

Luxury cruises in South America are all about the experience. Book one of the cruise deals below and you will have the opportunity to trek through wildlife-rich jungles, marvel at thundering waterfalls, visit ancient Incan ruins, and much more. Depending on the type of cruise you book, you may also get the chance to experience something truly unique, exclusively packaged up with luxury hotel stays and one-of-a-kind tours.

Find Out More About Cruising in South America


Filter
7 Night Galapagos Inner Loop Cruise
Baltra Island, Galápagos | Rabida Island | Puerto Egas | Elizabeth Bay, Isabela Island, Galápagos | Tagus Cove, Isabella Island, Galapagos | Bartolome Island | Sullivan Bay, Santiago Island, Galápagos | Daphne Major, Galapagos | North Seymour Island, Galapagos | Las Bachas, Santa Cruz Island, Galápagos | Punta Pitt, San Cristóbal Island, Galápagos | Puerto Baquerizo Moreno, San Cristobal Island, Galapagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
26 Oct 2025
7 Nights
Pacific

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £7686pp
Now: £6159
pp
REF: CELEBFL07G055-261025
Puerto Williams to Puerto Williams
Puerto Williams | Antarctic Sound | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | South Shetland Islands | Puerto Williams | Puerto Williams
26 Oct 2025
10 Nights
Antarctica

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £12200pp
Now: £11010
pp
REF: SILVERWI251026010
Caribbean & Amazon Icons
Boston, Massachusetts | Newport, Rhode Island | Hamilton | Hamilton | Saint George | Gustavia | Saint John's | Castries | Bridgetown | Saint George's | Kralendijk | Oranjestad | Miami, Florida | Saint John's | More...
27 Oct 2025
41 Nights
Caribbean

FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Ends 30th September - Last chance to book and receive a FREE house select beverage package
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £9769pp
Now: £8816
pp
REF: OCEANIAINS251027A
Magic of Colombia
Barranquilla | Nueva Venecia | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Calamar | Cartagena | Cartagena
29 Oct 2025
7 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £4492pp
Now: £4312
pp
REF: AMASB251029BC
12-Day Amazon Delta & Coast Of Brazil
Manaus | Manaus | Amazon Experience | Amazon Experience | Amazon Experience | Amazon Experience | Salvador de Bahia | Rio de Janeiro
30 Oct 2025
12 Nights
South America

EXCLUSIVE $600 to spend on-board* - must end 23rd September
Sail into Savings - Save up to 15% on selected Ocean and Expedition Voyages
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £6799pp
Now: £6007
pp
REF: SBNV557
40-Day From The Amazon To South Georgia & The Antarctic
Manaus | Manaus | Amazon Experience | Amazon Experience | Amazon Experience | Amazon Experience | Salvador de Bahia | Rio de Janeiro | Parati | Camboriú | Montevideo | Falkland Islands | Falkland Islands | Port Stanley | More...
30 Oct 2025
40 Nights
South America

EXCLUSIVE $600 to spend on-board* - must end 23rd September
Sail into Savings - Save up to 15% on selected Ocean and Expedition Voyages
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £21503pp
Now: £19000
pp
REF: SBNV557A
18-Day Chilean Fjords & Antarctica
San Antonio | Puerto Montt | Caleta Tortel | PIO X Glacier | El Brujo Glacier | Punta Arenas | Punta Arenas | Antarctic Experience | Antarctic Experience | Antarctic Experience | Antarctic Experience | Antarctic Experience | Buenos Aires | Ushuaia More...
30 Oct 2025
18 Nights
Antarctica

EXCLUSIVE $600 to spend on-board* - must end 23rd September
Sail into Savings - Save up to 15% on selected Ocean and Expedition Voyages
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £11898pp
Now: £10513
pp
REF: SBNP552
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | Bartolome Island | Santiago Island, Galápagos | Punta Vicente Roca, Isabela Island, Galápagos | Punta Espinoza, Fernandina Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Caleta Tagus | Champion Island, Galápagos | Post Office Bay, Floreana, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Santa Cruz Island, Galápagos | Isla Guy Fawkes, Galapagos | More...
01 Nov 2025
7 Nights
Pacific

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £10700pp
Now: £9656
pp
REF: SILVEROR251101007
Magic of Colombia
Barranquilla | Nueva Venecia | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Calamar | Cartagena | Cartagena
01 Nov 2025
7 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £4892pp
Now: £4696
pp
REF: AMASA251101BC
San Cristóbal, Galapagos to San Cristóbal, Galapagos
San Cristóbal Island, Galápagos | Roca León Dormido | Bartolome Island | Santiago Island, Galápagos | Punta Vicente Roca, Isabela Island, Galápagos | Punta Espinoza, Fernandina Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Caleta Tagus | Champion Island, Galápagos | Post Office Bay, Floreana, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Santa Cruz Island, Galápagos | Isla Guy Fawkes, Galapagos | More...
01 Nov 2025
14 Nights
South America

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £19100pp
Now: £17237
pp
REF: SILVEROR251101C14
In Shackleton's Footsteps
Ushuaia | Ushuaia | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Elephant Island, South Shetland Islands | South Georgia Island | South Georgia Island | South Georgia Island | South Georgia Island | South Georgia Island | Ushuaia
01 Nov 2025
19 Nights
Antarctica

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £16306pp
Now: £15816
pp
REF: AURORAASH002S
7 Night Galapagos Outer Loop Cruise
Baltra Island, Galápagos | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Floreana Island, Galapagos | Punta Cormorant, Floreana Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Urbina Bay, Isabella Island, Galapagos | Vincente Roca Point, Isabella Island, Galapagos | Punta Espinoza, Fernandina Island, Galápagos | Daphne Major, Galapagos | South Plaza Island, Galápagos | Dragon Hill, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
02 Nov 2025
7 Nights
Pacific

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £8416pp
Now: £6407
pp
REF: CELEBFL07G056-021125
Wonders of Colombia
Cartagena | Palenque | Calamar | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Barranquilla | Nueva Venecia | Barranquilla
05 Nov 2025
7 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £5568pp
Now: £5345
pp
REF: AMASB251105CB
Peruvian Amazon & Machu Picchu Exploration
Lima | Lima | Iquitos | Nauta | Nauta | Urubamba | Cusco | Cusco | Cusco | Lima | Lima
05 Nov 2025
15 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £13099pp
Now: £12575
pp
REF: UNIWORLD50625
Peruvian Rivers & Rainforest Discovery
Lima | Lima | Iquitos | Nauta | Nauta | Lima
05 Nov 2025
10 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £11899pp
Now: £11423
pp
REF: UNIWORLD50636
Puerto Williams to Puerto Williams
Puerto Williams | New Island | West Point Island | Port Stanley | South Georgia Island | South Georgia Island | South Georgia Island | Elephant Island, South Shetland Islands | Antarctic Sound | Antarctic Peninsula | Antarctic Peninsula | South Shetland Islands | Puerto Williams | Puerto Williams More...
05 Nov 2025
18 Nights
Antarctica

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £18700pp
Now: £16876
pp
REF: SILVERWI251105018
Wonders of Colombia
Cartagena | Palenque | Calamar | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Barranquilla | Nueva Venecia | Barranquilla
08 Nov 2025
7 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £5030pp
Now: £4829
pp
REF: AMASA251108CB
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | El Barranco, Genovesa Island, Galápagos | Darwin Bay, Genovesa Island, Galápagos | Sullivan Bay, Santiago Island, Galápagos | North Seymour Island, Galapagos | Punta Moreno, Isabella Island, Galapagos | Mangle Point, Fernandina Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Cerro Brujo, San Cristóbal Island, Galápagos | San Cristóbal Island, Galápagos | More...
08 Nov 2025
7 Nights
Pacific

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £10800pp
Now: £9747
pp
REF: SILVEROR251108007
Puerto Williams to Puerto Williams
Puerto Williams | New Island | West Point Island | Port Stanley | South Georgia Island | South Georgia Island | South Georgia Island | Elephant Island, South Shetland Islands | Antarctic Sound | Antarctic Peninsula | Antarctic Peninsula | South Shetland Islands | Puerto Williams | Puerto Williams More...
08 Nov 2025
18 Nights
Antarctica

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £18700pp
Now: £16876
pp
REF: SILVERE4251108018
7 Night Galapagos Inner Loop Cruise
Baltra Island, Galápagos | Rabida Island | Puerto Egas | Elizabeth Bay, Isabela Island, Galápagos | Tagus Cove, Isabella Island, Galapagos | Bartolome Island | Sullivan Bay, Santiago Island, Galápagos | Daphne Major, Galapagos | North Seymour Island, Galapagos | Las Bachas, Santa Cruz Island, Galápagos | Punta Pitt, San Cristóbal Island, Galápagos | Puerto Baquerizo Moreno, San Cristobal Island, Galapagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
09 Nov 2025
7 Nights
Pacific

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £7268pp
Now: £6392
pp
REF: CELEBFL07G055-091125
Spirit of Antarctica
Ushuaia | Ushuaia | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Ushuaia
10 Nov 2025
11 Nights
Antarctica

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £9954pp
Now: £9655
pp
REF: AURORAANP174G
Antarctica in Depth
Buenos Aires | Buenos Aires | Ushuaia | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Ushuaia | Buenos Aires | Ushuaia
11 Nov 2025
12 Nights
Antarctica

Celebrate 5 years of Scenic Ocean with an ADDITIONAL 5% off ALL sailings - Call for your extra savings
Save up to 30%, return flights included and free private door to door transfers*
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £16221pp
Now: £14867
pp
REF: SCENIC101S111125-1
28-Day Wild South Atlantic & Antarctica Peninsula
Rio de Janeiro | Parati | Camboriú | Montevideo | Falkland Islands | Falkland Islands | Port Stanley | South Georgia Experience | South Georgia Experience | South Georgia Experience | South Georgia Experience | South Georgia Experience | Antarctic Experience | Antarctic Experience | More...
11 Nov 2025
28 Nights
Antarctica

EXCLUSIVE $600 to spend on-board* - must end 23rd September
Sail into Savings - Save up to 15% on selected Ocean and Expedition Voyages
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £17083pp
Now: £15094
pp
REF: SBNV558
A Grand Journey of Coconut Breezes and Calypso Rhythms
Barcelona | Tangier | Las Palmas | Bridgetown | Pointe-à-Pitre | Saint John's | Charlotte Amalie | Miami, Florida
11 Nov 2025
17 Nights
Mediterranean

Sail Unique - Value savings included PLUS book with a low 10% deposit*
Penthouse Dream - Reserve an Ocean Penthouse and receive a complimentary one-category upgrade
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £4950pp
Now: £4702
pp
REF: EXPLORAEP20251111BCNMIA
Magic of Colombia
Barranquilla | Nueva Venecia | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Calamar | Cartagena | Cartagena
12 Nov 2025
7 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £5568pp
Now: £5345
pp
REF: AMASB251112BC

Explore South America on a Finest Collection voyage

Our Finest Collection cruise packages in South America offer tailor-made adventures exclusively for you. Your cruise is paired with a set of immersive land tours dedicated to helping you get right to the heart of the ports on your itinerary. What's more, after days spent hiking across glaciers or exploring iconic cities accompanied by a local tour guide, you can retire to a five-star hotel for a gourmet dinner and spot of well-earned relaxation. 

South America expedition cruises

If you want your South America cruise adventure to be even more unforgettable, embark on an expedition cruise and feel like a true explorer. Sailing to destinations like mysterious Easter Island, wild and rugged Chile, and the positively prehistoric Galapagos islands; once-in-a-lifetime experiences are guaranteed. Accompanied by a dedicated group of expedition experts - from marine biologists to professional adventurers - you willl live like an intrepid explorer and witness natural wonders most people can only dream of.

Book South America cruises with our Cruise Concierge team

If you would like to embark on an adventure you will never forget, call our Cruise Concierge team to book one of the itineraries below. And if you can't find exactly what you are looking for? Call us to build a completely bespoke cruise in South America that incorporates every port and experience you have been dreaming of.

Our Award Winning Service


Best Workplaces in Travel 2024
Best Workplaces in Travel 2024
TTG Luxury Cruise Agency Of The Year
TTG Luxury Cruise Agency Of The Year
Best Use Of Content 2023
Best Use Of Content 2023
Best Specialist Cruise Agent 2023
Best Specialist Cruise Agent 2023
UK Cruise Awards Winners 2023
UK Cruise Awards Winners 2023
Best Luxury Travel Agent 2022
Best Luxury Travel Agent 2022
Travel Weekly Large Cruise Agency of the Year 2023
Travel Weekly Large Cruise Agency of the Year 2023
Chat Service

Live Chat

Live Chat
Call for Free