Luxury South America Cruises

Luxury cruises in South America are all about the experience. Book one of the cruise deals below and you will have the opportunity to trek through wildlife-rich jungles, marvel at thundering waterfalls, visit ancient Incan ruins, and much more. Depending on the type of cruise you book, you may also get the chance to experience something truly unique, exclusively packaged up with luxury hotel stays and one-of-a-kind tours.

Find Out More About Cruising in South America


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Antarctic Triumph
San Antonio | Puerto Montt | Castro | Puerto Chacabuco | Laguna San Rafael National Park | Punta Arenas | Ushuaia | Port Stanley | Puerto Madryn | Buenos Aires
21 Dec 2025
20 Nights
Antarctica

FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Ends 30th September - Last chance to book and receive a FREE house select beverage package
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £7619pp
Now: £6876
pp
REF: OCEANIAMNA251221
Puerto Williams to Puerto Williams
Puerto Williams | New Island | West Point Island | Port Stanley | South Georgia Island | South Georgia Island | South Georgia Island | Elephant Island, South Shetland Islands | Antarctic Sound | Antarctic Peninsula | Antarctic Peninsula | South Shetland Islands | Puerto Williams | Puerto Williams More...
21 Dec 2025
18 Nights
Antarctica

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £21000pp
Now: £18952
pp
REF: SILVERWI251221018
11 Nt Panama Canal & Perfect Day Holiday
Fort Lauderdale, Florida | Cartagena | Colón | Oranjestad | Willemstad | Coco Cay | Fort Lauderdale, Florida
22 Dec 2025
11 Nights
Panama Canal

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £8030pp
Now: £7628
pp
REF: CELEBAT11C022-221225
Merriment & Joy In The Tropics
Miami, Florida | Basseterre, Saint Kitts | Saint John's | Fort-de-France | Bridgetown | Saint George's | Castries | Santa Marta | Miami, Florida
22 Dec 2025
12 Nights
Caribbean

Ultimate All-Inclusive Cruise Fare now includes: Round-trip Economy flights, transfers between airport and ship PLUS Private Executive Chauffeur Credit*
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £6709pp
Now: £6373
pp
REF: REGENTGRA251222
Fort Lauderdale to San Jose (Caldera)
Fort Lauderdale, Florida | Georgetown, Grand Cayman | Cartagena | Cartagena | Puerto Caldera
22 Dec 2025
8 Nights
Caribbean

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £3600pp
Now: £3492
pp
REF: CRYSTALCSE-008-251222
Fort Lauderdale to Los Angeles
Fort Lauderdale, Florida | Georgetown, Grand Cayman | Cartagena | Cartagena | Puerto Caldera | Huatulco (Santa María Huatulco) | Manzanillo, Mexico | La Paz | Cabo San Lucas | Isla Natividad | Los Angeles, California
22 Dec 2025
20 Nights
Caribbean

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £7700pp
Now: £7469
pp
REF: CRYSTALCSE-C20-251222
Puerto Williams to Puerto Williams
Puerto Williams | South Georgia Island | South Georgia Island | South Georgia Island | Elephant Island, South Shetland Islands | Antarctic Peninsula | Antarctic Peninsula | South Shetland Islands | Puerto Williams | Puerto Williams
22 Dec 2025
15 Nights
Antarctica

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £22100pp
Now: £19945
pp
REF: SILVEREV251222015
Magic of Colombia
Barranquilla | Nueva Venecia | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Calamar | Cartagena | Cartagena
24 Dec 2025
7 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £5038pp
Now: £4836
pp
REF: AMASB251224BC
Falklands, South Georgia & Antarctic Peninsula
Ushuaia | Ushuaia | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | South Georgia Island | South Georgia Island | South Georgia Island | South Georgia Island | South Georgia Island | South Georgia Island | Falkland Islands | Falkland Islands | More...
27 Dec 2025
22 Nights
Antarctica

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £21463pp
Now: £20819
pp
REF: AURORAFSP007G
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | Bartolome Island | Santiago Island, Galápagos | Punta Vicente Roca, Isabela Island, Galápagos | Punta Espinoza, Fernandina Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Caleta Tagus | Champion Island, Galápagos | Post Office Bay, Floreana, Galápagos | Punta Cormorant, Floreana Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Santa Cruz Island, Galápagos | More...
27 Dec 2025
7 Nights
Pacific

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £15200pp
Now: £13718
pp
REF: SILVEROR251227007
10-Day The Great White Continent
Buenos Aires | Ushuaia | Antarctic Experience | Antarctic Experience | Antarctic Experience | Antarctic Experience | Antarctic Experience | Buenos Aires | Ushuaia
28 Dec 2025
11 Nights
Antarctica

EXCLUSIVE $600 to spend on-board* - must end 23rd September
Sail into Savings - Save up to 15% on selected Ocean and Expedition Voyages
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £10228pp
Now: £9037
pp
REF: SBNV565
Buenos Aires to Valparaiso
Buenos Aires | Buenos Aires | Montevideo | Puerto Madryn | Port Stanley | Ushuaia | Punta Arenas | Chilean Fjords | Puerto Montt | Valparaiso | Valparaiso
28 Dec 2025
18 Nights
South America

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £10200pp
Now: £9205
pp
REF: SILVERWH251228018
7 Night Galapagos Outer Loop Cruise
Baltra Island, Galápagos | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Floreana Island, Galapagos | Punta Cormorant, Floreana Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Urbina Bay, Isabella Island, Galapagos | Vincente Roca Point, Isabella Island, Galapagos | Punta Espinoza, Fernandina Island, Galápagos | Daphne Major, Galapagos | South Plaza Island, Galápagos | Dragon Hill, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
28 Dec 2025
7 Nights
Pacific

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £10627pp
Now: £8537
pp
REF: CELEBFL07G056-281225
Antarctic Celebration
Buenos Aires | Puerto Madryn | Punta Arenas | Punta Arenas | Ushuaia | Port Stanley | Montevideo | Buenos Aires
28 Dec 2025
17 Nights
Antarctica

Ultimate All-Inclusive Cruise Fare now includes: Round-trip Economy flights, transfers between airport and ship PLUS Private Executive Chauffeur Credit*
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £12149pp
Now: £10964
pp
REF: REGENTSPL251228
Wonders of Colombia
Cartagena | Palenque | Calamar | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Barranquilla | Nueva Venecia | Barranquilla
03 Jan 2026
7 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £4538pp
Now: £4356
pp
REF: AMASA260103CB
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | El Barranco, Genovesa Island, Galápagos | Darwin Bay, Genovesa Island, Galápagos | Sullivan Bay, Santiago Island, Galápagos | North Seymour Island, Galapagos | Punta Moreno, Isabella Island, Galapagos | Mangle Point, Fernandina Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Cerro Brujo, San Cristóbal Island, Galápagos | San Cristóbal Island, Galápagos | More...
03 Jan 2026
7 Nights
Pacific

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £12200pp
Now: £11010
pp
REF: SILVEROR260103007
Tropical Escape Across The Canal
Miami, Florida | Georgetown, Grand Cayman | Ocho Rios | Kralendijk | Willemstad | Oranjestad | Cartagena | Puerto Limón | Panama City | Puntarenas | Corinto | Puerto Vallarta | Cabo San Lucas | Ensenada | More...
03 Jan 2026
22 Nights
Caribbean

Ultimate All-Inclusive Cruise Fare now includes: Round-trip Economy flights, transfers between airport and ship PLUS Private Executive Chauffeur Credit*
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £12519pp
Now: £11298
pp
REF: REGENTGRA260103A
Majestic Beaches & Canal Crossing
Miami, Florida | Georgetown, Grand Cayman | Ocho Rios | Kralendijk | Willemstad | Oranjestad | Cartagena | Puerto Limón | Panama City
03 Jan 2026
12 Nights
Caribbean

Ultimate All-Inclusive Cruise Fare now includes: Round-trip Economy flights, transfers between airport and ship PLUS Private Executive Chauffeur Credit*
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £7879pp
Now: £7110
pp
REF: REGENTGRA260103
14 Night Antarctica Cruise
Buenos Aires | Ushuaia | Gerlache Strait | Paradise Harbour | Elephant Island, South Shetland Islands | Port Stanley | Puerto Madryn | Montevideo | Buenos Aires
03 Jan 2026
14 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £12260pp
Now: £11647
pp
REF: CELEBEQ14F117-030126
Antarctica in Depth
Buenos Aires | Buenos Aires | Ushuaia | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Ushuaia | Buenos Aires | Ushuaia
04 Jan 2026
12 Nights
Antarctica

Celebrate 5 years of Scenic Ocean with an ADDITIONAL 5% off ALL sailings - Call for your extra savings
Save up to 30%, return flights included and free private door to door transfers*
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £15240pp
Now: £13236
pp
REF: SCENIC101S040126-1
7 Night Galapagos Inner Loop Cruise
Baltra Island, Galápagos | Rabida Island | Puerto Egas | Elizabeth Bay, Isabela Island, Galápagos | Tagus Cove, Isabella Island, Galapagos | Bartolome Island | Sullivan Bay, Santiago Island, Galápagos | Daphne Major, Galapagos | North Seymour Island, Galapagos | Las Bachas, Santa Cruz Island, Galápagos | Punta Pitt, San Cristóbal Island, Galápagos | Puerto Baquerizo Moreno, San Cristobal Island, Galapagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
04 Jan 2026
7 Nights
Pacific

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £6105pp
Now: £5568
pp
REF: CELEBFL07G057-040126
10-Day The Great White Continent
Buenos Aires | Ushuaia | Antarctic Experience | Antarctic Experience | Antarctic Experience | Antarctic Experience | Antarctic Experience | Buenos Aires | Ushuaia
05 Jan 2026
11 Nights
Antarctica

EXCLUSIVE $600 to spend on-board* - must end 23rd September
Sail into Savings - Save up to 15% on selected Ocean and Expedition Voyages
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £8923pp
Now: £7884
pp
REF: SBNP610
A Journey from Majestic Barrier Reefs to Mystical Jungle Ruins
Miami, Florida | San Andrés Island | Colón | Bocas del Toro | Puerto Limón | Georgetown, Grand Cayman | Miami, Florida
05 Jan 2026
10 Nights
Caribbean

Sail Unique - Value savings included PLUS book with a low 10% deposit*
Penthouse Dream - Reserve an Ocean Penthouse and receive a complimentary one-category upgrade
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £3800pp
Now: £3610
pp
REF: EXPLORAEP20260105MIAMIA
79-Night Circle South America Grand Voyage
Miami, Florida | Saint John Island | Charlotte Amalie | Philipsburg | Charlestown | Saint John's | Saint Pierre | Port Elizabeth, Bequia | Saint George's | Bridgetown | Scarborough | Isle Royale | Belem | Recife | More...
06 Jan 2026
79 Nights
South America

FLASH SALE - up to an ADDITIONAL $250 to spend on-board ENDS 22d September
Balconies and above receive: $300 FREE to spend on-board, Premium beverage package & unlimited wi-fi*
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £23219pp
Now: £21399
pp
REF: AZQS260106-079
Fort Lauderdale to Lima
Fort Lauderdale, Florida | Cozumel | Puerto Limón | Colón | Manta | Callao | Callao
06 Jan 2026
13 Nights
South America

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £11450pp
Now: £10333
pp
REF: SILVERDA260106013

Explore South America on a Finest Collection voyage

Our Finest Collection cruise packages in South America offer tailor-made adventures exclusively for you. Your cruise is paired with a set of immersive land tours dedicated to helping you get right to the heart of the ports on your itinerary. What's more, after days spent hiking across glaciers or exploring iconic cities accompanied by a local tour guide, you can retire to a five-star hotel for a gourmet dinner and spot of well-earned relaxation. 

South America expedition cruises

If you want your South America cruise adventure to be even more unforgettable, embark on an expedition cruise and feel like a true explorer. Sailing to destinations like mysterious Easter Island, wild and rugged Chile, and the positively prehistoric Galapagos islands; once-in-a-lifetime experiences are guaranteed. Accompanied by a dedicated group of expedition experts - from marine biologists to professional adventurers - you willl live like an intrepid explorer and witness natural wonders most people can only dream of.

Book South America cruises with our Cruise Concierge team

If you would like to embark on an adventure you will never forget, call our Cruise Concierge team to book one of the itineraries below. And if you can't find exactly what you are looking for? Call us to build a completely bespoke cruise in South America that incorporates every port and experience you have been dreaming of.

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