Luxury South America Cruises

Luxury cruises in South America are all about the experience. Book one of the cruise deals below and you will have the opportunity to trek through wildlife-rich jungles, marvel at thundering waterfalls, visit ancient Incan ruins, and much more. Depending on the type of cruise you book, you may also get the chance to experience something truly unique, exclusively packaged up with luxury hotel stays and one-of-a-kind tours.

Find Out More About Cruising in South America


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15-Night Central America Tapestry Voyage
Miami, Florida | Progreso | Progreso | Puerto Limón | Fuerte Amador | Fuerte Amador | Manta | Guayaquil | Trujillo | Callao | Callao
06 Jan 2026
15 Nights
Panama Canal

FLASH SALE - up to an ADDITIONAL $250 to spend on-board ENDS 22d September
Balconies and above receive: $300 FREE to spend on-board, Premium beverage package & unlimited wi-fi*
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £3889pp
Now: £3280
pp
REF: AZON260106-015
155-Night Azamara World Voyage
Miami, Florida | Progreso | Progreso | Puerto Limón | Fuerte Amador | Fuerte Amador | Manta | Guayaquil | Trujillo | Callao | Callao | Hangaroa, Easter Island | Hangaroa, Easter Island | Pitcairn Island | More...
06 Jan 2026
156 Nights
World-wide

FLASH SALE - up to an ADDITIONAL $250 to spend on-board ENDS 22d September
Balconies and above receive: $300 FREE to spend on-board, Premium beverage package & unlimited wi-fi*
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £35749pp
Now: £32946
pp
REF: AZON260106-155
Vibrant Voyage To Rio
Miami, Florida | Gustavia | Roseau | Bridgetown | Devil's Island | Belem | Fortaleza | Salvador de Bahia | Buzios | Rio de Janeiro | Rio de Janeiro
06 Jan 2026
18 Nights
South America

FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Ends 30th September - Last chance to book and receive a FREE house select beverage package
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £6869pp
Now: £6525
pp
REF: OCEANIAVIS260106
Circle South America
Miami, Florida | Gustavia | Roseau | Bridgetown | Devil's Island | Belem | Fortaleza | Salvador de Bahia | Buzios | Rio de Janeiro | Rio de Janeiro | Rio de Janeiro | Ilha Grande | Santos | More...
06 Jan 2026
60 Nights
South America

Ends 30th September - Last chance to book and receive a FREE house select beverage package
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £19249pp
Now: £18286
pp
REF: OCEANIAVIS260106C
Around The World In 180 Days
Miami, Florida | Gustavia | Roseau | Bridgetown | Devil's Island | Belem | Fortaleza | Salvador de Bahia | Buzios | Rio de Janeiro | Rio de Janeiro | Rio de Janeiro | Ilha Grande | Santos | More...
06 Jan 2026
180 Nights
World-wide

FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Ends 30th September - Last chance to book and receive a FREE house select beverage package
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £56839pp
Now: £53997
pp
REF: OCEANIAVIS260106J
Puerto Williams to Puerto Williams
Puerto Williams | New Island | West Point Island | Port Stanley | South Georgia Island | South Georgia Island | South Georgia Island | Elephant Island, South Shetland Islands | Antarctic Sound | Antarctic Peninsula | Antarctic Peninsula | South Shetland Islands | Puerto Williams | Puerto Williams More...
06 Jan 2026
18 Nights
Antarctica

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £31710pp
Now: £28609
pp
REF: SILVEREV260106018
Magic of Colombia
Barranquilla | Nueva Venecia | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Calamar | Cartagena | Cartagena
07 Jan 2026
7 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £5049pp
Now: £4847
pp
REF: AMASB260107BC
10-Day The Great White Continent
Buenos Aires | Ushuaia | Antarctic Experience | Antarctic Experience | Antarctic Experience | Antarctic Experience | Antarctic Experience | Buenos Aires | Ushuaia
07 Jan 2026
11 Nights
Antarctica

EXCLUSIVE $600 to spend on-board* - must end 23rd September
Sail into Savings - Save up to 15% on selected Ocean and Expedition Voyages
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £8668pp
Now: £7659
pp
REF: SBNV610
Magic of Colombia
Barranquilla | Nueva Venecia | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Calamar | Cartagena | Cartagena
10 Jan 2026
7 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £5529pp
Now: £5087
pp
REF: AMASA260110BC
South Georgia, Falklands & Antarctic Odyssey
Ushuaia | Ushuaia | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | South Georgia Island | South Georgia Island | South Georgia Island | South Georgia Island | South Georgia Island | Falkland Islands | Falkland Islands | Ushuaia More...
10 Jan 2026
20 Nights
Antarctica

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £20946pp
Now: £20317
pp
REF: AURORAASG096S
Bounty Of Brazil
Buenos Aires | Buenos Aires | Montevideo | Punta del Este | Itajai | Porto Belo | Santos | Parati | Ilha Grande | Buzios | Rio de Janeiro | Rio de Janeiro
10 Jan 2026
12 Nights
South America

FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Ends 30th September - Last chance to book and receive a FREE house select beverage package
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £5019pp
Now: £4529
pp
REF: OCEANIAMNA260110
The Sense Of Adventure
Miami, Florida | Miami, Florida | Cartagena | Puntarenas | Corinto | Puerto Quetzal | Acapulco | Cabo San Lucas | Hilo, Hawaii | Kahului-Maui, Hawaii | Honolulu, Hawaii | Honolulu, Hawaii | Nawiliwili, Hawaii | Nawiliwili, Hawaii | More...
10 Jan 2026
154 Nights
World-wide

Ultimate All-Inclusive Cruise Fare now includes: Round-trip Economy flights, transfers between airport and ship PLUS Private Executive Chauffeur Credit*
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £79019pp
Now: £71314
pp
REF: REGENTMAR260110H
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | Bartolome Island | Santiago Island, Galápagos | Punta Vicente Roca, Isabela Island, Galápagos | Punta Espinoza, Fernandina Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Caleta Tagus | Champion Island, Galápagos | Post Office Bay, Floreana, Galápagos | Punta Cormorant, Floreana Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Santa Cruz Island, Galápagos | More...
10 Jan 2026
7 Nights
Pacific

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £12200pp
Now: £11010
pp
REF: SILVEROR260110007
7 Night Galapagos Outer Loop Cruise
Baltra Island, Galápagos | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Floreana Island, Galapagos | Punta Cormorant, Floreana Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Urbina Bay, Isabella Island, Galapagos | Vincente Roca Point, Isabella Island, Galapagos | Punta Espinoza, Fernandina Island, Galápagos | Daphne Major, Galapagos | South Plaza Island, Galápagos | Dragon Hill, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
11 Jan 2026
7 Nights
Pacific

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £6569pp
Now: £5991
pp
REF: CELEBFL07G058-110126
Crossing Horizons
Miami, Florida | Cartagena | Puntarenas | Corinto | Puerto Quetzal | Acapulco | Cabo San Lucas | Hilo, Hawaii | Kahului-Maui, Hawaii | Honolulu, Hawaii | Honolulu, Hawaii
11 Jan 2026
21 Nights
Panama Canal

Ultimate All-Inclusive Cruise Fare now includes: Round-trip Economy flights, transfers between airport and ship PLUS Private Executive Chauffeur Credit*
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £14549pp
Now: £13130
pp
REF: REGENTMAR260111
Tropical Escapades, East To West
Miami, Florida | Cartagena | Puntarenas | Corinto | Puerto Quetzal | Acapulco | Cabo San Lucas | Hilo, Hawaii | Kahului-Maui, Hawaii | Honolulu, Hawaii | Honolulu, Hawaii | Nawiliwili, Hawaii | Nawiliwili, Hawaii | Lahaina, Hawaii | More...
11 Jan 2026
35 Nights
Panama Canal

Ultimate All-Inclusive Cruise Fare now includes: Round-trip Economy flights, transfers between airport and ship PLUS Private Executive Chauffeur Credit*
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £21694pp
Now: £19578
pp
REF: REGENTMAR260111A
Antarctica & The Chilean Fjords
Buenos Aires | Punta del Este | Port Stanley | Ushuaia | Punta Arenas | Laguna San Rafael National Park | Puerto Chacabuco | Puerto Montt | San Antonio
14 Jan 2026
18 Nights
Antarctica

Ultimate All-Inclusive Cruise Fare now includes: Round-trip Economy flights, transfers between airport and ship PLUS Private Executive Chauffeur Credit*
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £13029pp
Now: £11758
pp
REF: REGENTSPL260114
Antarctica in Depth
Buenos Aires | Buenos Aires | Ushuaia | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Ushuaia | Buenos Aires | Ushuaia
15 Jan 2026
12 Nights
Antarctica

Celebrate 5 years of Scenic Ocean with an ADDITIONAL 5% off ALL sailings - Call for your extra savings
Save up to 30%, return flights included and free private door to door transfers*
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £17211pp
Now: £14916
pp
REF: SCENIC101S150126-1
10-Day The Great White Continent
Buenos Aires | Ushuaia | Antarctic Experience | Antarctic Experience | Antarctic Experience | Antarctic Experience | Antarctic Experience | Buenos Aires | Ushuaia
15 Jan 2026
11 Nights
Antarctica

EXCLUSIVE $600 to spend on-board* - must end 23rd September
Sail into Savings - Save up to 15% on selected Ocean and Expedition Voyages
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £9603pp
Now: £8485
pp
REF: SBNP612
Valparaiso to Buenos Aires
Valparaiso | Valparaiso | Puerto Montt | Chilean Fjords | Punta Arenas | Ushuaia | Ushuaia | Port Stanley | Puerto Madryn | Montevideo | Buenos Aires | Buenos Aires
15 Jan 2026
18 Nights
South America

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £9200pp
Now: £8303
pp
REF: SILVERWH260115018
Island & Amazon Immersion
Miami, Florida | Oranjestad | Willemstad | Port-of-Spain | Saint George's | Castries | Kingstown | Roseau | Fort-de-France | Bridgetown | Santarém | Parintins | Manaus | Manaus | More...
15 Jan 2026
31 Nights
South America

FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Ends 30th September - Last chance to book and receive a FREE house select beverage package
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £9229pp
Now: £8329
pp
REF: OCEANIAINS260115A
Tropical Tastes Of The Riviera
Panama City | Puntarenas | Corinto | Puerto Vallarta | Cabo San Lucas | Ensenada | Los Angeles, California
15 Jan 2026
10 Nights
South America

Ultimate All-Inclusive Cruise Fare now includes: Round-trip Economy flights, transfers between airport and ship PLUS Private Executive Chauffeur Credit*
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £6679pp
Now: £6027
pp
REF: REGENTGRA260115
10-Day The Great White Continent
Buenos Aires | Ushuaia | Antarctic Experience | Antarctic Experience | Antarctic Experience | Antarctic Experience | Antarctic Experience | Buenos Aires | Ushuaia
17 Jan 2026
11 Nights
Antarctica

EXCLUSIVE $600 to spend on-board* - must end 23rd September
Sail into Savings - Save up to 15% on selected Ocean and Expedition Voyages
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £8668pp
Now: £7659
pp
REF: SBNV611
Antarctic Explorer Express
Ushuaia | Ushuaia | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | King George Island, South Shetland Islands | Punta Arenas
17 Jan 2026
8 Nights
Antarctica

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £9566pp
Now: £9279
pp
REF: AURORAANE003G
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | El Barranco, Genovesa Island, Galápagos | Darwin Bay, Genovesa Island, Galápagos | Sullivan Bay, Santiago Island, Galápagos | North Seymour Island, Galapagos | Punta Moreno, Isabella Island, Galapagos | Mangle Point, Fernandina Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Cerro Brujo, San Cristóbal Island, Galápagos | San Cristóbal Island, Galápagos | More...
17 Jan 2026
7 Nights
Pacific

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £12200pp
Now: £11010
pp
REF: SILVEROR260117007

Explore South America on a Finest Collection voyage

Our Finest Collection cruise packages in South America offer tailor-made adventures exclusively for you. Your cruise is paired with a set of immersive land tours dedicated to helping you get right to the heart of the ports on your itinerary. What's more, after days spent hiking across glaciers or exploring iconic cities accompanied by a local tour guide, you can retire to a five-star hotel for a gourmet dinner and spot of well-earned relaxation. 

South America expedition cruises

If you want your South America cruise adventure to be even more unforgettable, embark on an expedition cruise and feel like a true explorer. Sailing to destinations like mysterious Easter Island, wild and rugged Chile, and the positively prehistoric Galapagos islands; once-in-a-lifetime experiences are guaranteed. Accompanied by a dedicated group of expedition experts - from marine biologists to professional adventurers - you willl live like an intrepid explorer and witness natural wonders most people can only dream of.

Book South America cruises with our Cruise Concierge team

If you would like to embark on an adventure you will never forget, call our Cruise Concierge team to book one of the itineraries below. And if you can't find exactly what you are looking for? Call us to build a completely bespoke cruise in South America that incorporates every port and experience you have been dreaming of.

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