Luxury South America Cruises

Luxury cruises in South America are all about the experience. Book one of the cruise deals below and you will have the opportunity to trek through wildlife-rich jungles, marvel at thundering waterfalls, visit ancient Incan ruins, and much more. Depending on the type of cruise you book, you may also get the chance to experience something truly unique, exclusively packaged up with luxury hotel stays and one-of-a-kind tours.

Find Out More About Cruising in South America


Filter
Edge Of The World Expedition
San Antonio | Puerto Montt | Puerto Chacabuco | Laguna San Rafael National Park | Punta Arenas | Ushuaia | Ushuaia | Puerto Madryn | Montevideo | Buenos Aires
01 Feb 2026
16 Nights
South America

Ultimate All-Inclusive Cruise Fare now includes: Round-trip Economy flights, transfers between airport and ship PLUS Private Executive Chauffeur Credit*
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £11529pp
Now: £10404
pp
REF: REGENTSPL260201
Buenos Aires to Rio de Janeiro
Buenos Aires | Buenos Aires | Punta del Este | Balneário de Camboriú | Paranaguá | Ilhabela | Ilha Grande | Buzios | Rio de Janeiro | Rio de Janeiro
02 Feb 2026
12 Nights
South America

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £6700pp
Now: £6046
pp
REF: SILVERWH260202012
11 Nt Panama Canal & Southern Caribbean
Fort Lauderdale, Florida | Cartagena | Colón | Oranjestad | Willemstad | Georgetown, Grand Cayman | Fort Lauderdale, Florida
02 Feb 2026
11 Nights
Panama Canal

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £4286pp
Now: £4071
pp
REF: CELEBAT11C023-020226
Around Cape Horn
Buenos Aires | Montevideo | Port Stanley | Ushuaia | Punta Arenas | Puerto Montt | Valparaiso | Coquimbo | Iquique | Pisco | Callao
03 Feb 2026
18 Nights
South America

FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Ends 30th September - Last chance to book and receive a FREE house select beverage package
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £7589pp
Now: £6849
pp
REF: OCEANIAVIS260203
Cartagena to Bridgetown
Cartagena | Santa Marta | Oranjestad | Oranjestad | Kralendijk | Willemstad | Soufrière | Port Elizabeth, Bequia | Bridgetown
03 Feb 2026
9 Nights
Caribbean

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £6400pp
Now: £5776
pp
REF: SILVERSS260203009
Cartagena to Philipsburg, St. Maarten
Cartagena | Santa Marta | Oranjestad | Oranjestad | Kralendijk | Willemstad | Soufrière | Port Elizabeth, Bequia | Bridgetown | Bridgetown | Trois-Ilets | Kingstown | Roseau | Gustavia | More...
03 Feb 2026
16 Nights
Caribbean

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £7300pp
Now: £6588
pp
REF: SILVERSS260203C16
Magic of Colombia
Barranquilla | Nueva Venecia | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Calamar | Cartagena | Cartagena
04 Feb 2026
7 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £4938pp
Now: £4740
pp
REF: AMASB260204BC
EXCLUSIVE OFFER - Thrill of Antarctica with Machu Picchu
Puerto Williams | South Georgia Island | South Georgia Island | South Georgia Island | Elephant Island, South Shetland Islands | Antarctic Peninsula | Antarctic Peninsula | South Shetland Islands | Puerto Williams | Puerto Williams
05 Feb 2026
26 Nights
Antarctica

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
HOLIDAY PRICES FROM

Now: £16499
pp
REF: SILVERWI260207015-2

Finest Collection

Puerto Williams to Puerto Williams
Puerto Williams | Antarctic Sound | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | South Shetland Islands | Puerto Williams | Puerto Williams
05 Feb 2026
10 Nights
Antarctica

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £14300pp
Now: £12905
pp
REF: SILVEREV260205010
10-Day The Great White Continent
Buenos Aires | Ushuaia | Antarctic Experience | Antarctic Experience | Antarctic Experience | Antarctic Experience | Antarctic Experience | Buenos Aires | Ushuaia
06 Feb 2026
11 Nights
Antarctica

EXCLUSIVE $600 to spend on-board* - must end 23rd September
Sail into Savings - Save up to 15% on selected Ocean and Expedition Voyages
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £8668pp
Now: £7659
pp
REF: SBNP616
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | Bartolome Island | Santiago Island, Galápagos | Punta Vicente Roca, Isabela Island, Galápagos | Punta Espinoza, Fernandina Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Caleta Tagus | Champion Island, Galápagos | Post Office Bay, Floreana, Galápagos | Punta Cormorant, Floreana Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Santa Cruz Island, Galápagos | More...
07 Feb 2026
7 Nights
Pacific

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £12200pp
Now: £11010
pp
REF: SILVEROR260207007
Puerto Williams to Puerto Williams
Puerto Williams | South Georgia Island | South Georgia Island | South Georgia Island | Elephant Island, South Shetland Islands | Antarctic Peninsula | Antarctic Peninsula | South Shetland Islands | Puerto Williams | Puerto Williams
07 Feb 2026
15 Nights
Antarctica

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £17300pp
Now: £15613
pp
REF: SILVERWI260207015
10-Day The Great White Continent
Buenos Aires | Ushuaia | Antarctic Experience | Antarctic Experience | Antarctic Experience | Antarctic Experience | Antarctic Experience | Buenos Aires | Ushuaia
08 Feb 2026
11 Nights
Antarctica

EXCLUSIVE $600 to spend on-board* - must end 23rd September
Sail into Savings - Save up to 15% on selected Ocean and Expedition Voyages
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £8668pp
Now: £7659
pp
REF: SBNV616
Antarctic Peninsula: Fly the Drake
Punta Arenas | Punta Arenas | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | King George Island, South Shetland Islands | Punta Arenas
08 Feb 2026
11 Nights
Antarctica

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £16743pp
Now: £16240
pp
REF: AURORAAPF011S
Epic Antarctica: Crossing the 7th Continent
Dunedin | Dunedin | Macquarie Island, Tasmania | Macquarie Island, Tasmania | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Ushuaia
08 Feb 2026
33 Nights
Antarctica

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £28317pp
Now: £27467
pp
REF: AURORAASC001D
7 Night Galapagos Outer Loop Cruise
Baltra Island, Galápagos | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Floreana Island, Galapagos | Punta Cormorant, Floreana Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Urbina Bay, Isabella Island, Galapagos | Vincente Roca Point, Isabella Island, Galapagos | Punta Espinoza, Fernandina Island, Galápagos | Daphne Major, Galapagos | South Plaza Island, Galápagos | Dragon Hill, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
08 Feb 2026
7 Nights
Pacific

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £6697pp
Now: £6108
pp
REF: CELEBFL07G058-080226
22-Night Southern Quest Voyage
Buenos Aires | Montevideo | Punta del Este | Port Stanley | Antarctic Sound | Antarctic Sound | Antarctic Sound | Ushuaia | Ushuaia | Punta Arenas | Chilean Fjords | Chilean Fjords | Puerto Chacabuco | Castro | More...
08 Feb 2026
22 Nights
South America

FLASH SALE - up to an ADDITIONAL $250 to spend on-board ENDS 22d September
Balconies and above receive: $300 FREE to spend on-board, Premium beverage package & unlimited wi-fi*
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £7399pp
Now: £6459
pp
REF: AZQS260208-022
Leeward Islands Odyssey
Miami, Florida | Great Stirrup Cay | San Juan (Puerto Rico) | Tortola | Gustavia | Saint John's | Castries | Santa Marta | Miami, Florida
10 Feb 2026
11 Nights
Caribbean

Ultimate All-Inclusive Cruise Fare now includes: Round-trip Economy flights, transfers between airport and ship PLUS Private Executive Chauffeur Credit*
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £6779pp
Now: £6118
pp
REF: REGENTGRA260210
Antarctica in Depth
Buenos Aires | Buenos Aires | Ushuaia | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Ushuaia | Buenos Aires | Ushuaia
13 Feb 2026
12 Nights
Antarctica

Celebrate 5 years of Scenic Ocean with an ADDITIONAL 5% off ALL sailings - Call for your extra savings
Save up to 30%, return flights included and free private door to door transfers*
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £17211pp
Now: £15719
pp
REF: SCENIC101S130226-1
Wonders of Colombia
Cartagena | Palenque | Calamar | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Barranquilla | Nueva Venecia | Barranquilla
14 Feb 2026
7 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £5523pp
Now: £5302
pp
REF: AMASA260214CB
Rio de Janeiro to Buenos Aires
Rio de Janeiro | Rio de Janeiro | Rio de Janeiro | Buzios | Ilhabela | Paranaguá | Balneário de Camboriú | Punta del Este | Buenos Aires | Buenos Aires | Buenos Aires
14 Feb 2026
12 Nights
South America

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £6700pp
Now: £6046
pp
REF: SILVERWH260214012
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | El Barranco, Genovesa Island, Galápagos | Darwin Bay, Genovesa Island, Galápagos | Sullivan Bay, Santiago Island, Galápagos | North Seymour Island, Galapagos | Punta Moreno, Isabella Island, Galapagos | Mangle Point, Fernandina Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Cerro Brujo, San Cristóbal Island, Galápagos | San Cristóbal Island, Galápagos | More...
14 Feb 2026
7 Nights
Pacific

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £12400pp
Now: £11780
pp
REF: SILVEROR260214007
14 Night Patagonia & Argentina Cruise
Buenos Aires | Montevideo | Port Stanley | Ushuaia | Punta Arenas | Puerto Madryn | Punta del Este | Buenos Aires
14 Feb 2026
14 Nights
South America

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £7953pp
Now: £7555
pp
REF: CELEBEQ14F115-140226
7 Night Galapagos Inner Loop Cruise
Baltra Island, Galápagos | Rabida Island | Puerto Egas | Elizabeth Bay, Isabela Island, Galápagos | Tagus Cove, Isabella Island, Galapagos | Bartolome Island | Sullivan Bay, Santiago Island, Galápagos | Daphne Major, Galapagos | North Seymour Island, Galapagos | Las Bachas, Santa Cruz Island, Galápagos | Punta Pitt, San Cristóbal Island, Galápagos | Puerto Baquerizo Moreno, San Cristobal Island, Galapagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
15 Feb 2026
7 Nights
Pacific

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £6583pp
Now: £6004
pp
REF: CELEBFL07G057-150226
Spectacular Antarctica
San Antonio | Puerto Montt | Castro | Puerto Chacabuco | Punta Arenas | Ushuaia | Port Stanley | Puerto Madryn | Buenos Aires | Buenos Aires
15 Feb 2026
20 Nights
Antarctica

FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Ends 30th September - Last chance to book and receive a FREE house select beverage package
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £7389pp
Now: £6668
pp
REF: OCEANIAMNA260215

Explore South America on a Finest Collection voyage

Our Finest Collection cruise packages in South America offer tailor-made adventures exclusively for you. Your cruise is paired with a set of immersive land tours dedicated to helping you get right to the heart of the ports on your itinerary. What's more, after days spent hiking across glaciers or exploring iconic cities accompanied by a local tour guide, you can retire to a five-star hotel for a gourmet dinner and spot of well-earned relaxation. 

South America expedition cruises

If you want your South America cruise adventure to be even more unforgettable, embark on an expedition cruise and feel like a true explorer. Sailing to destinations like mysterious Easter Island, wild and rugged Chile, and the positively prehistoric Galapagos islands; once-in-a-lifetime experiences are guaranteed. Accompanied by a dedicated group of expedition experts - from marine biologists to professional adventurers - you willl live like an intrepid explorer and witness natural wonders most people can only dream of.

Book South America cruises with our Cruise Concierge team

If you would like to embark on an adventure you will never forget, call our Cruise Concierge team to book one of the itineraries below. And if you can't find exactly what you are looking for? Call us to build a completely bespoke cruise in South America that incorporates every port and experience you have been dreaming of.

Our Award Winning Service


Best Workplaces in Travel 2024
Best Workplaces in Travel 2024
TTG Luxury Cruise Agency Of The Year
TTG Luxury Cruise Agency Of The Year
Best Use Of Content 2023
Best Use Of Content 2023
Best Specialist Cruise Agent 2023
Best Specialist Cruise Agent 2023
UK Cruise Awards Winners 2023
UK Cruise Awards Winners 2023
Best Luxury Travel Agent 2022
Best Luxury Travel Agent 2022
Travel Weekly Large Cruise Agency of the Year 2023
Travel Weekly Large Cruise Agency of the Year 2023

Request a Callback