Luxury South America Cruises

Luxury cruises in South America are all about the experience. Book one of the cruise deals below and you will have the opportunity to trek through wildlife-rich jungles, marvel at thundering waterfalls, visit ancient Incan ruins, and much more. Depending on the type of cruise you book, you may also get the chance to experience something truly unique, exclusively packaged up with luxury hotel stays and one-of-a-kind tours.

Find Out More About Cruising in South America


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Magic of Colombia
Barranquilla | Nueva Venecia | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Calamar | Cartagena | Cartagena
01 Apr 2026
7 Nights
South America

SixStarCruises Exotic Sale Event - Save up to £400 per couple*
Fly Cruise From
Was £4938pp
Now: £4740
pp
REF: AMASB260401BC
19-Day Easter & Pitcairn Islands: Marooned, Moai & Mutineers
San Antonio | Hangaroa, Easter Island | Hangaroa, Easter Island | Ducie Island | Pitcairn Island | Fakarava | Toau Atoll | Anaa | Papeete, Tahiti
02 Apr 2026
19 Nights
Pacific

EXTENDED UNTIL 12th November - Save up to 15%* - book before prices increase!
SixStarCruises Exotic Sale Event - Save up to £400 per couple*
Cruise Only From
Was £11159pp
Now: £10489
pp
REF: SBNP625
30-Day Across Oceanic Cultures: Chilean Coast To Fiji
San Antonio | Hangaroa, Easter Island | Hangaroa, Easter Island | Ducie Island | Pitcairn Island | Fakarava | Toau Atoll | Anaa | Papeete, Tahiti | Raiatea | Aitutaki | Apia | Vava'u | Nuku'alofa | More...
02 Apr 2026
30 Nights
Pacific

EXTENDED UNTIL 12th November - Save up to 15%* - book before prices increase!
SixStarCruises Exotic Sale Event - Save up to £400 per couple*
Cruise Only From
Was £15029pp
Now: £14127
pp
REF: SBNP625A
46-Day Remote Islands Of The Pacific & New Guinea
San Antonio | Hangaroa, Easter Island | Hangaroa, Easter Island | Ducie Island | Pitcairn Island | Fakarava | Toau Atoll | Anaa | Papeete, Tahiti | Raiatea | Aitutaki | Apia | Vava'u | Nuku'alofa | More...
02 Apr 2026
46 Nights
Pacific

EXTENDED UNTIL 12th November - Save up to 15%* - book before prices increase!
SixStarCruises Exotic Sale Event - Save up to £400 per couple*
Cruise Only From
Was £22499pp
Now: £21149
pp
REF: SBNP625B
56-Day Remote Islands Of The Pacific & Kimberley Expedition
San Antonio | Hangaroa, Easter Island | Hangaroa, Easter Island | Ducie Island | Pitcairn Island | Fakarava | Toau Atoll | Anaa | Papeete, Tahiti | Raiatea | Aitutaki | Apia | Vava'u | Nuku'alofa | More...
02 Apr 2026
56 Nights
Pacific

EXTENDED UNTIL 12th November - Save up to 15%* - book before prices increase!
SixStarCruises Exotic Sale Event - Save up to £400 per couple*
Cruise Only From
Was £27449pp
Now: £25802
pp
REF: SBNP625C
Magic of Colombia
Barranquilla | Nueva Venecia | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Calamar | Cartagena | Cartagena
04 Apr 2026
7 Nights
South America

SixStarCruises Exotic Sale Event - Save up to £400 per couple*
Fly Cruise From
Was £4938pp
Now: £4740
pp
REF: AMASA260404BC
21-Day Brazil Coast, Cape Verde & Canary Islands Crossing
Rio de Janeiro | Salvador de Bahia | Recife | Natal | Praia, Santiago Island | Mindelo, São Vicente Island | Tenerife | Arrecife, Lanzarote | Casablanca | Barcelona
04 Apr 2026
21 Nights
South America

EXTENDED UNTIL 12th November - Save up to 15%* - book before prices increase!
SixStarCruises Exotic Sale Event - Save up to £400 per couple*
Cruise Only From
Was £7649pp
Now: £7190
pp
REF: SBNV626
31-Day Brazil, Cape Verde, Canary Islands & Riviera Harbors
Rio de Janeiro | Salvador de Bahia | Recife | Natal | Praia, Santiago Island | Mindelo, São Vicente Island | Tenerife | Arrecife, Lanzarote | Casablanca | Barcelona | Sète | Cassis | Saint-Tropez | Nice | More...
04 Apr 2026
31 Nights
South America

EXTENDED UNTIL 12th November - Save up to 15%* - book before prices increase!
SixStarCruises Exotic Sale Event - Save up to £400 per couple*
Cruise Only From
Was £12509pp
Now: £11758
pp
REF: SBNV626A
Classic Canal & Tropics
Panama City | Cartagena | Willemstad | Oranjestad | Montego Bay | Georgetown, Grand Cayman | Miami, Florida
04 Apr 2026
10 Nights
Panama Canal

Your World Included - FREE gratuities, FREE gourmet speciality dining, FREE unlimited Wi-Fi and FREE soft drinks including speciality teas & coffees
Caribbean Sale - Enjoy included flights PLUS 5% bonus savings
SixStarCruises Exotic Sale Event - Save up to £400 per couple*
Book now with a 2-4-1 deposit!
Fly Cruise From
Was £3969pp
Now: £3730
pp
REF: OCEANIAINS260404
7 Night Galapagos Outer Loop Cruise
Baltra Island, Galápagos | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Floreana Island, Galapagos | Punta Cormorant, Floreana Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Urbina Bay, Isabella Island, Galapagos | Vincente Roca Point, Isabella Island, Galapagos | Punta Espinoza, Fernandina Island, Galápagos | Daphne Major, Galapagos | South Plaza Island, Galápagos | Dragon Hill, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
05 Apr 2026
7 Nights
Pacific

SixStarCruises Exotic Sale Event - Save up to £400 per couple*
Cruise Only From
Was £6583pp
Now: £5824
pp
REF: CELEBFL07G058-050426
19-Day Panama Canal Passage
Long Beach, California | Puerto Vallarta | Huatulco (Santa María Huatulco) | Puerto Chiapas | Puerto Quetzal | Puntarenas | Cartagena | Miami, Florida
07 Apr 2026
19 Nights
Panama Canal

EXTENDED UNTIL 12th November - Save up to 15%* - book before prices increase!
SixStarCruises Exotic Sale Event - Save up to £400 per couple*
Cruise Only From
Was £5579pp
Now: £5244
pp
REF: SBN6626
Wonders of Colombia
Cartagena | Palenque | Calamar | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Barranquilla | Nueva Venecia | Barranquilla
08 Apr 2026
7 Nights
South America

SixStarCruises Exotic Sale Event - Save up to £400 per couple*
Fly Cruise From
Was £5084pp
Now: £4881
pp
REF: AMASB260408CB
7 Night Galapagos Inner Loop Cruise
Baltra Island, Galápagos | Rabida Island | Puerto Egas | Elizabeth Bay, Isabela Island, Galápagos | Tagus Cove, Isabella Island, Galapagos | Bartolome Island | Sullivan Bay, Santiago Island, Galápagos | Daphne Major, Galapagos | North Seymour Island, Galapagos | Las Bachas, Santa Cruz Island, Galápagos | Punta Pitt, San Cristóbal Island, Galápagos | Puerto Baquerizo Moreno, San Cristobal Island, Galapagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
12 Apr 2026
7 Nights
Pacific

SixStarCruises Exotic Sale Event - Save up to £400 per couple*
Cruise Only From
Was £6721pp
Now: £6365
pp
REF: CELEBFL07G057-120426
Panama Canal & the Alluring Islands of the Caribbean
Panama City | Portobelo | Cayos Limon | Cartagena | Aruba | Curaçao | Curaçao | Tobago Cays | Bridgetown
13 Apr 2026
11 Nights
Caribbean

Experience the voyage of a lifetime in 6-star ultra-luxury on board Scenic Eclipse, The World’s First Discovery Yachts
SixStarCruises Exotic Sale Event - Save up to £400 per couple*
Fly Cruise From
Was £8860pp
Now: £8505
pp
REF: SCENIC121C130426-1
Magic of Colombia
Barranquilla | Nueva Venecia | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Calamar | Cartagena | Cartagena
15 Apr 2026
7 Nights
South America

SixStarCruises Exotic Sale Event - Save up to £400 per couple*
Fly Cruise From
Was £4938pp
Now: £4740
pp
REF: AMASB260415BC
Magic of Colombia
Barranquilla | Nueva Venecia | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Calamar | Cartagena | Cartagena
18 Apr 2026
7 Nights
South America

SixStarCruises Exotic Sale Event - Save up to £400 per couple*
Fly Cruise From
Was £4938pp
Now: £4740
pp
REF: AMASA260418BC
7 Night Galapagos Outer Loop Cruise
Baltra Island, Galápagos | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Floreana Island, Galapagos | Punta Cormorant, Floreana Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Urbina Bay, Isabella Island, Galapagos | Vincente Roca Point, Isabella Island, Galapagos | Punta Espinoza, Fernandina Island, Galápagos | Daphne Major, Galapagos | South Plaza Island, Galápagos | Dragon Hill, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
19 Apr 2026
7 Nights
Pacific

SixStarCruises Exotic Sale Event - Save up to £400 per couple*
Cruise Only From
Was £7249pp
Now: £6714
pp
REF: CELEBFL07G058-190426
Wonders of Colombia
Cartagena | Palenque | Calamar | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Barranquilla | Nueva Venecia | Barranquilla
22 Apr 2026
7 Nights
South America

SixStarCruises Exotic Sale Event - Save up to £400 per couple*
Fly Cruise From
Was £4938pp
Now: £4740
pp
REF: AMASB260422CB
Natural Treasures of Costa Rica
San José | San José | Manuel Antonio National Park | Punta Rio Claro National Wildlife Refuge | Punta Leona | Curú Wildlife Refuge | Punta Arenas
23 Apr 2026
6 Nights
South America

SixStarCruises Exotic Sale Event - Save up to £400 per couple*
Cruise Only From
Was £4421pp
Now: £4288
pp
REF: AURORANCR001S
Canal & Coral Isles
Panama City | Cartagena | Puerto Limón | Roatán Island | Costa Maya | Cozumel | Miami, Florida
24 Apr 2026
10 Nights
Panama Canal

Your World Included - FREE gratuities, FREE gourmet speciality dining, FREE unlimited Wi-Fi and FREE soft drinks including speciality teas & coffees
Caribbean Sale - Enjoy included flights PLUS 5% bonus savings
SixStarCruises Exotic Sale Event - Save up to £400 per couple*
Book now with a 2-4-1 deposit!
Fly Cruise From
Was £3829pp
Now: £3599
pp
REF: OCEANIAINS260424
Wonders of Colombia
Cartagena | Palenque | Calamar | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Barranquilla | Nueva Venecia | Barranquilla
25 Apr 2026
7 Nights
South America

SixStarCruises Exotic Sale Event - Save up to £400 per couple*
Fly Cruise From
Was £4938pp
Now: £4740
pp
REF: AMASA260425CB
7 Night Galapagos Inner Loop Cruise
Baltra Island, Galápagos | Rabida Island | Puerto Egas | Elizabeth Bay, Isabela Island, Galápagos | Tagus Cove, Isabella Island, Galapagos | Bartolome Island | Sullivan Bay, Santiago Island, Galápagos | Daphne Major, Galapagos | North Seymour Island, Galapagos | Las Bachas, Santa Cruz Island, Galápagos | Punta Pitt, San Cristóbal Island, Galápagos | Puerto Baquerizo Moreno, San Cristobal Island, Galapagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
26 Apr 2026
7 Nights
Pacific

SixStarCruises Exotic Sale Event - Save up to £400 per couple*
Cruise Only From
Was £6890pp
Now: £6387
pp
REF: CELEBFL07G057-260426
Magic of Colombia
Barranquilla | Nueva Venecia | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Calamar | Cartagena | Cartagena
29 Apr 2026
7 Nights
South America

SixStarCruises Exotic Sale Event - Save up to £400 per couple*
Fly Cruise From
Was £4938pp
Now: £4740
pp
REF: AMASB260429BC
Magic of Colombia
Barranquilla | Nueva Venecia | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Calamar | Cartagena | Cartagena
02 May 2026
7 Nights
South America

SixStarCruises Exotic Sale Event - Save up to £400 per couple*
Fly Cruise From
Was £4938pp
Now: £4740
pp
REF: AMASA260502BC
7 Night Galapagos Outer Loop Cruise
Baltra Island, Galápagos | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Floreana Island, Galapagos | Punta Cormorant, Floreana Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Urbina Bay, Isabella Island, Galapagos | Vincente Roca Point, Isabella Island, Galapagos | Punta Espinoza, Fernandina Island, Galápagos | Daphne Major, Galapagos | South Plaza Island, Galápagos | Dragon Hill, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
03 May 2026
7 Nights
Pacific

SixStarCruises Exotic Sale Event - Save up to £400 per couple*
Cruise Only From
Was £7639pp
Now: £6850
pp
REF: CELEBFL07G058-030526

Explore South America on a Finest Collection voyage

Our Finest Collection cruise packages in South America offer tailor-made adventures exclusively for you. Your cruise is paired with a set of immersive land tours dedicated to helping you get right to the heart of the ports on your itinerary. What's more, after days spent hiking across glaciers or exploring iconic cities accompanied by a local tour guide, you can retire to a five-star hotel for a gourmet dinner and spot of well-earned relaxation. 

South America expedition cruises

If you want your South America cruise adventure to be even more unforgettable, embark on an expedition cruise and feel like a true explorer. Sailing to destinations like mysterious Easter Island, wild and rugged Chile, and the positively prehistoric Galapagos islands; once-in-a-lifetime experiences are guaranteed. Accompanied by a dedicated group of expedition experts - from marine biologists to professional adventurers - you willl live like an intrepid explorer and witness natural wonders most people can only dream of.

Book South America cruises with our Cruise Concierge team

If you would like to embark on an adventure you will never forget, call our Cruise Concierge team to book one of the itineraries below. And if you can't find exactly what you are looking for? Call us to build a completely bespoke cruise in South America that incorporates every port and experience you have been dreaming of.

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