Luxury South America Cruises

Luxury cruises in South America are all about the experience. Book one of the cruise deals below and you will have the opportunity to trek through wildlife-rich jungles, marvel at thundering waterfalls, visit ancient Incan ruins, and much more. Depending on the type of cruise you book, you may also get the chance to experience something truly unique, exclusively packaged up with luxury hotel stays and one-of-a-kind tours.

Find Out More About Cruising in South America


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Antarctic & Patagonian Joy
Callao | Pisco | Coquimbo | San Antonio | Puerto Montt | Puerto Chacabuco | Laguna San Rafael National Park | Punta Arenas | Ushuaia | Port Stanley | Punta del Este | Buenos Aires | Buenos Aires
21 Dec 2024
24 Nights
Antarctica

FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Fly Cruise From
Was £7719pp
Now: £6966
pp
REF: OCEANIAMNA241221
Captivating South America
Callao | Pisco | Coquimbo | San Antonio | Puerto Montt | Puerto Chacabuco | Laguna San Rafael National Park | Punta Arenas | Ushuaia | Port Stanley | Punta del Este | Buenos Aires | Buenos Aires | Buenos Aires | More...
21 Dec 2024
36 Nights
South America

FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Fly Cruise From
Was £11939pp
Now: £10774
pp
REF: OCEANIAMNA241221A
Bridgetown to Fort Lauderdale
Bridgetown | Scarborough | Castries | Port Elizabeth, Bequia | Willemstad | Oranjestad | Cartagena | Cartagena | Colón | Roatán Island | Belize City | Cozumel | Fort Lauderdale, Florida
21 Dec 2024
16 Nights
Caribbean

$300 FREE to spend on-board - ONLY when booking with SixStarCruises
Save £2400 per couple
Fly Cruise From
Was £9300pp
Now: £8393
pp
REF: SILVERMO241221016
Bridgetown to Cartagena
Bridgetown | Scarborough | Castries | Port Elizabeth, Bequia | Willemstad | Oranjestad | Cartagena
21 Dec 2024
8 Nights
Caribbean

Save £2400 per couple
Cruise Only From
Was £4300pp
Now: £3880
pp
REF: SILVERMO241221S08
Puerto Williams to King George Island
Puerto Williams | Port Stanley | New Island | West Point Island | South Georgia Island | South Georgia Island | South Georgia Island | Antarctic Sound | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | King George Island, South Shetland Islands
22 Dec 2024
15 Nights
Antarctica

Save £2400 per couple
Fly Cruise From
Was £29200pp
Now: £27740
pp
REF: SILVEREV241222015
11 Night Canal & Caribbean Holiday
Fort Lauderdale, Florida | Cartagena | Colón | Willemstad | Oranjestad | Georgetown, Grand Cayman | Fort Lauderdale, Florida
23 Dec 2024
11 Nights
Panama Canal

Fly Cruise From
Was £5148pp
Now: £4890
pp
REF: CELEBBY11C018-231224
New Year In The Tropics
Miami, Florida | Port Antonio | Oranjestad | Willemstad | Kralendijk | Charlestown | Santa Marta | Tortola | San Juan (Puerto Rico)
23 Dec 2024
11 Nights
Caribbean

Ultimate All-Inclusive Cruise Fare now includes: Round-trip Economy flights, transfers between airport and ship PLUS Private Executive Chauffeur Credit*
Fly Cruise From
Was £6019pp
Now: £5718
pp
REF: REGENTNAV241223
Beyond The Panama Canal
Miami, Florida | Great Stirrup Cay | Cartagena | Puntarenas | Corinto | Puerto Quetzal | Acapulco | Cabo San Lucas | Ensenada | Los Angeles, California
23 Dec 2024
16 Nights
Panama Canal

Olife Choice AVAILABLE ON EVERY BOOKING - $800 to spend on-board OR 8 FREE shore excursions or FREE beverage package
HUGE savings, FREE pre-paid gratuities worth up to $23pppd & FREE on-board spend - EXCLUSIVE to SixStarCruises
Fly Cruise From
Was £4459pp
Now: £3537
pp
REF: OCEANIANAU241223
Cartagena to Lima
Cartagena | Manta | Callao | Callao
27 Dec 2024
8 Nights
South America

Save £2400 per couple
Cruise Only From
Was £10600pp
Now: £10070
pp
REF: SILVERRA241227S08
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | Bartolome Island | Santiago Island, Galápagos | Punta Vicente Roca, Isabela Island, Galápagos | Punta Espinoza, Fernandina Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Caleta Tagus | Champion Island, Galápagos | Post Office Bay, Floreana, Galápagos | Punta Cormorant, Floreana Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Santa Cruz Island, Galápagos | More...
28 Dec 2024
7 Nights
Pacific

Save £2400 per couple
Fly Cruise From
Was £13900pp
Now: £13205
pp
REF: SILVEROR241228007
Cartagena to Fort Lauderdale
Cartagena | Cartagena | Colón | Roatán Island | Belize City | Cozumel | Fort Lauderdale, Florida
29 Dec 2024
8 Nights
Caribbean

Save £2400 per couple
Cruise Only From
Was £5050pp
Now: £4557
pp
REF: SILVERMO241229S08
7 Night Galapagos Outer Loop Cruise
Baltra Island, Galápagos | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Floreana Island, Galapagos | Punta Cormorant, Floreana Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Urbina Bay, Isabella Island, Galapagos | Vincente Roca Point, Isabella Island, Galapagos | Punta Espinoza, Fernandina Island, Galápagos | Daphne Major, Galapagos | South Plaza Island, Galápagos | Dragon Hill, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
29 Dec 2024
7 Nights
Pacific

Cruise Only From
Was £11373pp
Now: £5962
pp
REF: CELEBFL07G046-291224
Puerto Williams to Puerto Williams
Puerto Williams | South Georgia Island | South Georgia Island | South Georgia Island | Elephant Island, South Shetland Islands | Antarctic Peninsula | Antarctic Peninsula | South Shetland Islands | Puerto Williams | Puerto Williams
29 Dec 2024
15 Nights
Antarctica

Save £2400 per couple
Fly Cruise From
Was £17000pp
Now: £15342
pp
REF: SILVERE4241229015
South Georgia & Antarctic Odyssey
Ushuaia | Ushuaia | Falkland Islands | South Georgia Island | South Georgia Island | South Georgia Island | South Georgia Island | South Georgia Island | South Georgia Island | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | King George Island, South Shetland Islands | More...
02 Jan 2025
19 Nights
Antarctica

Cruise Only From
Was £32455pp
Now: £31481
pp
REF: AURORAASG094S
South America and the Panama Canal - Lima to Fort Lauderdale
Callao | Callao | Guayaquil | Panama City | Cartagena | Cartagena | Oranjestad | Fort Lauderdale, Florida
04 Jan 2025
16 Nights
South America

$300 FREE to spend on-board - ONLY when booking with SixStarCruises
Limited time 10% savings included
Save £2400 per couple
Fly Cruise From
Was £8400pp
Now: £5577
pp
REF: SILVERRA250104016
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | El Barranco, Genovesa Island, Galápagos | Darwin Bay, Genovesa Island, Galápagos | Sullivan Bay, Santiago Island, Galápagos | North Seymour Island, Galapagos | Punta Moreno, Isabella Island, Galapagos | Mangle Point, Fernandina Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Cerro Brujo, San Cristóbal Island, Galápagos | San Cristóbal Island, Galápagos | More...
04 Jan 2025
7 Nights
Pacific

Save £2400 per couple
Fly Cruise From
Was £19800pp
Now: £18810
pp
REF: SILVEROR250104007
Hamburg to Rio De Janeiro
Hamburg | Amsterdam | Rotterdam | Zeebrugge | Southampton | Praia da Vitória | Port Canaveral, Florida | Fort Lauderdale, Florida | Grand Turk Island | Bridgetown | Fortaleza | Salvador de Bahia | Buzios | Rio de Janeiro | More...
04 Jan 2025
33 Nights
South America

FLASH SALE - 10% off 2025 voyages* - CALL us for your flash sale price!
Fly Cruise From
Was £10149pp
Now: £9946
pp
REF: CUNARDV502D
Lima to Fuerte Amador
Callao | Callao | Guayaquil | Panama City
04 Jan 2025
7 Nights
South America

Save £2400 per couple
Cruise Only From
Was £2900pp
Now: £2617
pp
REF: SILVERRA250104S07
Amazon Trailblazer
Bridgetown | Scarborough | Santarém | Boca de Valeria | Manaus | Manaus | Parintins | Alter do Chão | Devil's Island | Saint George's | Îles des Saintes | Rodney Bay | Bridgetown
04 Jan 2025
18 Nights
South America

FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Fly Cruise From
Was £6639pp
Now: £5991
pp
REF: OCEANIASIR250104
Around The World In 180 Days
Miami, Florida | Philipsburg | Roseau | Bridgetown | Alter do Chão | Parintins | Manaus | Manaus | Boca de Valeria | Santarém | Salvador de Bahia | Rio de Janeiro | Rio de Janeiro | Montevideo | More...
05 Jan 2025
180 Nights
World-wide

FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Fly Cruise From
Was £45689pp
Now: £41234
pp
REF: OCEANIAINS250105G
Global Horizons
Miami, Florida | Philipsburg | Roseau | Bridgetown | Alter do Chão | Parintins | Manaus | Manaus | Boca de Valeria | Santarém | Salvador de Bahia | Rio de Janeiro | Rio de Janeiro | Montevideo | More...
05 Jan 2025
196 Nights
World-wide

FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Fly Cruise From
Was £50269pp
Now: £45367
pp
REF: OCEANIAINS250105H
Kaleidoscope Of Your World
Miami, Florida | Philipsburg | Roseau | Bridgetown | Alter do Chão | Parintins | Manaus | Manaus | Boca de Valeria | Santarém | Salvador de Bahia | Rio de Janeiro | Rio de Janeiro | Montevideo | More...
05 Jan 2025
200 Nights
World-wide

FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Fly Cruise From
Was £50269pp
Now: £45367
pp
REF: OCEANIAINS250105I
Antilles To Amazon
Miami, Florida | Philipsburg | Roseau | Bridgetown | Alter do Chão | Parintins | Manaus | Manaus | Boca de Valeria | Santarém | Salvador de Bahia | Rio de Janeiro | Rio de Janeiro
05 Jan 2025
22 Nights
South America

FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Fly Cruise From
Was £6989pp
Now: £6307
pp
REF: OCEANIAINS250105
Atlantic Ocean Delight
Cape Town | Lüderitz | Walvis Bay | Walvis Bay | Jamestown | Rio de Janeiro | Rio de Janeiro
05 Jan 2025
14 Nights
Atlantic Islands

Ultimate All-Inclusive Cruise Fare now includes: Round-trip Economy flights, transfers between airport and ship PLUS Private Executive Chauffeur Credit*
Fly Cruise From
Was £6119pp
Now: £5522
pp
REF: REGENTSPL250105
Passageways To Wonder
Cape Town | Lüderitz | Walvis Bay | Walvis Bay | Jamestown | Rio de Janeiro | Rio de Janeiro | Ilha Grande | Santos | Itajai | Montevideo | Buenos Aires | Buenos Aires | Punta del Este | More...
05 Jan 2025
38 Nights
World-wide

Ultimate All-Inclusive Cruise Fare now includes: Round-trip Economy flights, transfers between airport and ship PLUS Private Executive Chauffeur Credit*
Fly Cruise From
Was £20969pp
Now: £18924
pp
REF: REGENTSPL250105A

Explore South America on a Finest Collection voyage

Our Finest Collection cruise packages in South America offer tailor-made adventures exclusively for you. Your cruise is paired with a set of immersive land tours dedicated to helping you get right to the heart of the ports on your itinerary. What's more, after days spent hiking across glaciers or exploring iconic cities accompanied by a local tour guide, you can retire to a five-star hotel for a gourmet dinner and spot of well-earned relaxation. 

South America expedition cruises

If you want your South America cruise adventure to be even more unforgettable, embark on an expedition cruise and feel like a true explorer. Sailing to destinations like mysterious Easter Island, wild and rugged Chile, and the positively prehistoric Galapagos islands; once-in-a-lifetime experiences are guaranteed. Accompanied by a dedicated group of expedition experts - from marine biologists to professional adventurers - you willl live like an intrepid explorer and witness natural wonders most people can only dream of.

Book South America cruises with our Cruise Concierge team

If you would like to embark on an adventure you will never forget, call our Cruise Concierge team to book one of the itineraries below. And if you can't find exactly what you are looking for? Call us to build a completely bespoke cruise in South America that incorporates every port and experience you have been dreaming of.

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