Luxury South America Cruises

Luxury cruises in South America are all about the experience. Book one of the cruise deals below and you will have the opportunity to trek through wildlife-rich jungles, marvel at thundering waterfalls, visit ancient Incan ruins, and much more. Depending on the type of cruise you book, you may also get the chance to experience something truly unique, exclusively packaged up with luxury hotel stays and one-of-a-kind tours.

Find Out More About Cruising in South America


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Puerto Williams to Puerto Williams
Puerto Williams | Antarctic Sound | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | South Shetland Islands | Puerto Williams | Puerto Williams
05 Jan 2025
10 Nights
Antarctica

Limited time 10% savings included
Save £2400 per couple
Fly Cruise From
Was £18500pp
Now: £13944
pp
REF: SILVERWI250105010
Spirit of Antarctica
Ushuaia | Ushuaia | South Shetland Islands | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Ushuaia
06 Jan 2025
11 Nights
Antarctica

Cruise Only From
Was £11829pp
Now: £11474
pp
REF: AURORAANP172G
King George Island to Puerto Williams
King George Island, South Shetland Islands | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Sound | South Georgia Island | South Georgia Island | South Georgia Island | Port Stanley | New Island | West Point Island | Puerto Williams | Puerto Williams
06 Jan 2025
15 Nights
Antarctica

Save £2400 per couple
Fly Cruise From
Was £43100pp
Now: £28500
pp
REF: SILVEREV250106015
Navigate The World (Away In Wonder)
Miami, Florida | Miami, Florida | Roseau | Bridgetown | Devil's Island | Belem | Recife | Maceió | Salvador de Bahia | Buzios | Rio de Janeiro | Rio de Janeiro | Santos | Itajai | More...
07 Jan 2025
150 Nights
World-wide

Ultimate All-Inclusive Cruise Fare now includes: Round-trip Economy flights, transfers between airport and ship PLUS Private Executive Chauffeur Credit*
Fly Cruise From
Was £82309pp
Now: £74283
pp
REF: REGENTMAR250107H
Navigate The World (Away In Wonder)
Miami, Florida | Miami, Florida | Roseau | Bridgetown | Devil's Island | Belem | Recife | Maceió | Salvador de Bahia | Buzios | Rio de Janeiro | Rio de Janeiro | Santos | Itajai | More...
07 Jan 2025
168 Nights
World-wide

Ultimate All-Inclusive Cruise Fare now includes: Round-trip Economy flights, transfers between airport and ship PLUS Private Executive Chauffeur Credit*
Fly Cruise From
Was £91829pp
Now: £82875
pp
REF: REGENTMAR250107I
16-Night Colombia, Ecuador & Peru Voyage
Miami, Florida | Oranjestad | Kralendijk | Willemstad | Cartagena | Cartagena | Manta | Guayaquil | Trujillo | Callao | Callao
07 Jan 2025
16 Nights
South America

Two-night luxury hotel stay included when booking with SixStarCruises
Cruise Only From
Was £3725pp
Now: £2759
pp
REF: AZJR16T094-070125
Fort Lauderdale to Lima (Callao)
Fort Lauderdale, Florida | Georgetown, Grand Cayman | Costa Maya | Belize City | Roatán Island | Cartagena | Cartagena | Fuerte Amador | Manta | Guayaquil | Guayaquil | Salaverry | Callao
07 Jan 2025
18 Nights
Caribbean

Cruise Only From
Was £7550pp
Now: £7323
pp
REF: CRYSTALCSE-018-250107
Ft. Lauderdale to Barcelona
Fort Lauderdale, Florida | Georgetown, Grand Cayman | Costa Maya | Belize City | Roatán Island | Cartagena | Cartagena | Fuerte Amador | Manta | Guayaquil | Guayaquil | Salaverry | Callao | Callao | More...
07 Jan 2025
123 Nights
World-wide

Cruise Only From
Was £54400pp
Now: £52768
pp
REF: CRYSTALCSE-W122-250107
Panama Canal Adventure
Miami, Florida | Georgetown, Grand Cayman | Cartagena | Puntarenas | Corinto | Puerto Quetzal | Acapulco | Cabo San Lucas | Ensenada | Los Angeles, California
08 Jan 2025
16 Nights
Panama Canal

Receive up to a four-category stateroom upgrade*!
FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Fly Cruise From
Was £7339pp
Now: £6972
pp
REF: OCEANIAVIS250108
Ultimate Snowbird Paradise
Miami, Florida | Georgetown, Grand Cayman | Cartagena | Puntarenas | Corinto | Puerto Quetzal | Acapulco | Cabo San Lucas | Ensenada | Los Angeles, California | Ensenada | Cabo San Lucas | Acapulco | Puerto Quetzal | More...
08 Jan 2025
90 Nights
World-wide

FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Fly Cruise From
Was £31739pp
Now: £28644
pp
REF: OCEANIAVIS250108G
Iguazu Falls with Tango & Samba Celebration Cruise
Buenos Aires | Buenos Aires | Montevideo | Montevideo | Itajai | São Francisco do Sul | Santos | Parati | Ilha Grande | Buzios | Rio de Janeiro | Rio de Janeiro
09 Jan 2025
18 Nights
South America

FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
HOLIDAY PRICES FROM

Now: £5099
pp
REF: OCEANIAMNA250114-2

Finest Collection

South America Discovery
Southampton | Praia da Vitória | Port Canaveral, Florida | Fort Lauderdale, Florida | Grand Turk Island | Bridgetown | Fortaleza | Salvador de Bahia | Buzios | Rio de Janeiro | Rio de Janeiro | Montevideo | Buenos Aires | Buenos Aires | More...
09 Jan 2025
78 Nights
World-wide

Departs from the UK
Cruise Only From
Was £116599pp
Now: £110839
pp
REF: CUNARDV503B
Southampton to Rio De Janeiro
Southampton | Praia da Vitória | Port Canaveral, Florida | Fort Lauderdale, Florida | Grand Turk Island | Bridgetown | Fortaleza | Salvador de Bahia | Buzios | Rio de Janeiro | Rio de Janeiro
09 Jan 2025
28 Nights
South America

FLASH SALE - 10% off 2025 voyages* - CALL us for your flash sale price!
Fly Cruise From
Was £10029pp
Now: £9828
pp
REF: CUNARDV503A
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | Bartolome Island | Santiago Island, Galápagos | Punta Vicente Roca, Isabela Island, Galápagos | Punta Espinoza, Fernandina Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Caleta Tagus | Champion Island, Galápagos | Post Office Bay, Floreana, Galápagos | Punta Cormorant, Floreana Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Santa Cruz Island, Galápagos | More...
11 Jan 2025
7 Nights
Pacific

Save £2400 per couple
Fly Cruise From
Was £13500pp
Now: £12825
pp
REF: SILVEROR250111007
Fuerte Amador to Fort Lauderdale
Panama City | Cartagena | Cartagena | Oranjestad | Fort Lauderdale, Florida
11 Jan 2025
9 Nights
South America

Save £2400 per couple
Cruise Only From
Was £4050pp
Now: £3655
pp
REF: SILVERRA250111S09
11 Night Panama Canal & S. Caribbean
Fort Lauderdale, Florida | Cartagena | Colón | Oranjestad | Willemstad | Kralendijk | Fort Lauderdale, Florida
13 Jan 2025
11 Nights
Panama Canal

Fly Cruise From
Was £2932pp
Now: £2166
pp
REF: CELEBBY11C019-130125
Joy Of The Islands
San Juan (Puerto Rico) | Charlotte Amalie | Santa Marta | Roseau | Castries | Saint John's | Gustavia | San Juan (Puerto Rico)
13 Jan 2025
7 Nights
Caribbean

Ultimate All-Inclusive Cruise Fare now includes: Round-trip Economy flights, transfers between airport and ship PLUS Private Executive Chauffeur Credit*
Fly Cruise From
Was £4519pp
Now: £4078
pp
REF: REGENTNAV250113
Puerto Williams to Puerto Williams
Puerto Williams | Antarctic Sound | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | South Shetland Islands | Puerto Williams | Puerto Williams
13 Jan 2025
10 Nights
Antarctica

Save £2400 per couple
Fly Cruise From
Was £14700pp
Now: £13266
pp
REF: SILVERE4250113010
Tango & Samba Celebration
Buenos Aires | Buenos Aires | Montevideo | Montevideo | Itajai | São Francisco do Sul | Santos | Parati | Ilha Grande | Buzios | Rio de Janeiro | Rio de Janeiro
14 Jan 2025
12 Nights
South America

FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Fly Cruise From
Was £4829pp
Now: £4358
pp
REF: OCEANIAMNA250114
Puerto Williams to Puerto Williams
Puerto Williams | Antarctic Sound | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | South Shetland Islands | Puerto Williams | Puerto Williams
15 Jan 2025
10 Nights
Antarctica

Save £2400 per couple
Fly Cruise From
Was £14100pp
Now: £12725
pp
REF: SILVERWI250115010
Machu Picchu with Peru & Chile Voyage
Callao | Callao | Pisco | Arica | Iquique | Antarctic Sound | Coquimbo | San Antonio | San Antonio
17 Jan 2025
17 Nights
South America

Hidden Gems Sale - $500 to spend on board | Book a Veranda or Suite to get unlimited Wi-Fi or a Premium Beverage Package
FLASH SALE - Save up to £1,500* - ENDS 13th September
Two-night luxury hotel stay included when booking with SixStarCruises
HOLIDAY PRICES FROM
Was £5249pp
Now: £3899
pp
REF: AZJR10F010-230125-2

Finest Collection

Wonders of Colombia
Cartagena | Palenque | Calamar | Pinto | Santa Cruz de Mompox | Santa Cruz de Mompox | Santa Cruz de Mompox | El Banco | Magangué | Barranquilla | Nueva Venecia | Barranquilla
18 Jan 2025
7 Nights
South America

Fly Cruise From
Was £4714pp
Now: £4525
pp
REF: AMASA250118CB
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | El Barranco, Genovesa Island, Galápagos | Darwin Bay, Genovesa Island, Galápagos | Sullivan Bay, Santiago Island, Galápagos | North Seymour Island, Galapagos | Punta Moreno, Isabella Island, Galapagos | Mangle Point, Fernandina Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Cerro Brujo, San Cristóbal Island, Galápagos | San Cristóbal Island, Galápagos | More...
18 Jan 2025
7 Nights
Pacific

Save £2400 per couple
Fly Cruise From
Was £12400pp
Now: £11191
pp
REF: SILVEROR250118007
San Cristóbal, Galapagos to San Cristóbal, Galapagos
San Cristóbal Island, Galápagos | Roca León Dormido | El Barranco, Genovesa Island, Galápagos | Darwin Bay, Genovesa Island, Galápagos | Sullivan Bay, Santiago Island, Galápagos | North Seymour Island, Galapagos | Punta Moreno, Isabella Island, Galapagos | Mangle Point, Fernandina Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Cerro Brujo, San Cristóbal Island, Galápagos | San Cristóbal Island, Galápagos | More...
18 Jan 2025
14 Nights
South America

Save £2400 per couple
Fly Cruise From
Was £20000pp
Now: £18050
pp
REF: SILVEROR250118C14
Antarctic Explorer
Punta Arenas | King George Island, South Shetland Islands | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Ushuaia
19 Jan 2025
12 Nights
Antarctica

Cruise Only From
Was £17778pp
Now: £17244
pp
REF: AURORAAEP046S

Explore South America on a Finest Collection voyage

Our Finest Collection cruise packages in South America offer tailor-made adventures exclusively for you. Your cruise is paired with a set of immersive land tours dedicated to helping you get right to the heart of the ports on your itinerary. What's more, after days spent hiking across glaciers or exploring iconic cities accompanied by a local tour guide, you can retire to a five-star hotel for a gourmet dinner and spot of well-earned relaxation. 

South America expedition cruises

If you want your South America cruise adventure to be even more unforgettable, embark on an expedition cruise and feel like a true explorer. Sailing to destinations like mysterious Easter Island, wild and rugged Chile, and the positively prehistoric Galapagos islands; once-in-a-lifetime experiences are guaranteed. Accompanied by a dedicated group of expedition experts - from marine biologists to professional adventurers - you willl live like an intrepid explorer and witness natural wonders most people can only dream of.

Book South America cruises with our Cruise Concierge team

If you would like to embark on an adventure you will never forget, call our Cruise Concierge team to book one of the itineraries below. And if you can't find exactly what you are looking for? Call us to build a completely bespoke cruise in South America that incorporates every port and experience you have been dreaming of.

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