Luxury South America Cruises

Luxury cruises in South America are all about the experience. Book one of the cruise deals below and you will have the opportunity to trek through wildlife-rich jungles, marvel at thundering waterfalls, visit ancient Incan ruins, and much more. Depending on the type of cruise you book, you may also get the chance to experience something truly unique, exclusively packaged up with luxury hotel stays and one-of-a-kind tours.

Find Out More About Cruising in South America


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Peruvian Rivers & Rainforest Discovery
Lima | Lima | Iquitos | Nauta | Nauta | Lima
19 Feb 2025
10 Nights
South America

Fly Cruise From
Was £9799pp
Now: £9407
pp
REF: UNIWORLD50627
Antarctic Explorer
Punta Arenas | King George Island, South Shetland Islands | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Ushuaia
20 Feb 2025
11 Nights
Antarctica

Cruise Only From
Was £11681pp
Now: £11330
pp
REF: AURORAAEP049S
Buenos Aires to Rio de Janeiro
Buenos Aires | Buenos Aires | Montevideo | Punta del Este | Balneário de Camboriú | Ilhabela | Rio de Janeiro | Rio de Janeiro | Rio de Janeiro
21 Feb 2025
10 Nights
South America

$200 FREE to spend on-board - ONLY when booking with SixStarCruises
Save £2400 per couple
Fly Cruise From
Was £9600pp
Now: £9120
pp
REF: SILVERRA250221010
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | Bartolome Island | Santiago Island, Galápagos | Punta Vicente Roca, Isabela Island, Galápagos | Punta Espinoza, Fernandina Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Caleta Tagus | Champion Island, Galápagos | Post Office Bay, Floreana, Galápagos | Punta Cormorant, Floreana Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Santa Cruz Island, Galápagos | More...
22 Feb 2025
7 Nights
Pacific

Save £2400 per couple
Fly Cruise From
Was £10300pp
Now: £9295
pp
REF: SILVEROR250222007
Buenos Aires to Rio de Janeiro
Buenos Aires | Balneário de Camboriú | São Francisco do Sul | Santos | Santos | Ilhabela | Angra dos Reis | Rio de Janeiro | Rio de Janeiro | Rio de Janeiro
22 Feb 2025
11 Nights
South America

Cruise Only From
Was £5400pp
Now: £5238
pp
REF: CRYSTALCSE-011-250222
Puerto Williams to Puerto Williams
Puerto Williams | New Island | West Point Island | Port Stanley | South Georgia Island | South Georgia Island | South Georgia Island | Elephant Island, South Shetland Islands | Antarctic Sound | Antarctic Peninsula | Antarctic Peninsula | South Shetland Islands | Puerto Williams | Puerto Williams More...
22 Feb 2025
18 Nights
Antarctica

Limited time 10% savings included
Save £2400 per couple
Fly Cruise From
Was £21600pp
Now: £16462
pp
REF: SILVERWI250222018
Puerto Williams to Cape Town
Puerto Williams | New Island | West Point Island | Port Stanley | South Georgia Island | South Georgia Island | South Georgia Island | Elephant Island, South Shetland Islands | Antarctic Sound | Antarctic Peninsula | Antarctic Peninsula | South Shetland Islands | Puerto Williams | Puerto Williams | More...
22 Feb 2025
40 Nights
Antarctica

Save £2400 per couple
Fly Cruise From
Was £24300pp
Now: £21930
pp
REF: SILVERWI250222C40
Across the Antarctic Circle
Ushuaia | Ushuaia | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Ushuaia
23 Feb 2025
12 Nights
Antarctica

Cruise Only From
Was £11559pp
Now: £11212
pp
REF: AURORAANC012G
7 Night Galapagos Outer Loop Cruise
Baltra Island, Galápagos | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Floreana Island, Galapagos | Punta Cormorant, Floreana Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Urbina Bay, Isabella Island, Galapagos | Vincente Roca Point, Isabella Island, Galapagos | Punta Espinoza, Fernandina Island, Galápagos | Daphne Major, Galapagos | South Plaza Island, Galápagos | Dragon Hill, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
23 Feb 2025
7 Nights
Pacific

Cruise Only From
Was £15001pp
Now: £13681
pp
REF: CELEBFL07G056-230225
11 Night Panama Canal & S. Caribbean
Fort Lauderdale, Florida | Cartagena | Colón | Oranjestad | Willemstad | Kralendijk | Fort Lauderdale, Florida
24 Feb 2025
11 Nights
Panama Canal

Fly Cruise From
Was £7296pp
Now: £6931
pp
REF: CELEBBY11C019-240225
25-Night Carnival Rio & Amazon Voyage
Buenos Aires | Buenos Aires | Montevideo | Rio de Janeiro | Rio de Janeiro | Rio de Janeiro | Salvador de Bahia | Macapa | Alter do Chão | Manaus | Manaus | Parintins | Santarém | Macapa | More...
25 Feb 2025
25 Nights
South America

Hidden Gems Sale - $500 to spend on board | Book a Veranda or Suite to get unlimited Wi-Fi or a Premium Beverage Package
Amazing prices you just cant miss - very limited availability at these prices
Cruise Only From
Was £8499pp
Now: £8259
pp
REF: AZJR25F001-250225
San Antonio to Fort Lauderdale
San Antonio | Coquimbo | Arica | Callao | Callao | Manta | Aruba | Nassau | Fort Lauderdale, Florida
25 Feb 2025
17 Nights
South America

FLASH SALE - 10% off 2025 voyages* - CALL us for your flash sale price!
Fly Cruise From
Was £10469pp
Now: £10259
pp
REF: CUNARDV506
San Antonio to Southampton
San Antonio | Coquimbo | Arica | Callao | Callao | Manta | Aruba | Nassau | Fort Lauderdale, Florida | Port Canaveral, Florida | Hamilton | Ponta Delgada, Azores | Southampton
25 Feb 2025
31 Nights
South America

FLASH SALE - 10% off 2025 voyages* - CALL us for your flash sale price!
Fly Cruise From
Was £12869pp
Now: £12611
pp
REF: CUNARDV506A
20-Day Antarctica & Chilean Fjords
Buenos Aires | Ushuaia | Antarctic Experience | Antarctic Experience | Antarctic Experience | Antarctic Experience | Antarctic Experience | Garibaldi Glacier | Punta Arenas | Fjord of the Mountains | PIO X Glacier | Caleta Tortel | Caleta Tortel | Castro | More...
25 Feb 2025
21 Nights
Antarctica

Cruise Only From
Was £12397pp
Now: £10953
pp
REF: SBNP518
Puerto Williams to Puerto Williams
Puerto Williams | Antarctic Sound | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | South Shetland Islands | Puerto Williams | Puerto Williams
26 Feb 2025
12 Nights
Antarctica

Save £2400 per couple
Fly Cruise From
Was £16200pp
Now: £14620
pp
REF: SILVEREV250226012
Puerto Williams to Puerto Williams
Puerto Williams | Antarctic Sound | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | South Shetland Islands | Puerto Williams | Puerto Williams
27 Feb 2025
10 Nights
Antarctica

Save £2400 per couple
Fly Cruise From
Was £15200pp
Now: £13718
pp
REF: SILVERE4250227010
Antarctica, Argentina & Brazil - Cruise & Land journey
Buenos Aires | Buenos Aires | Ushuaia | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | South Georgia Island | South Georgia Island | South Georgia Island | South Georgia Island | Falkland Islands | More...
28 Feb 2025
31 Nights
South America

Experience the voyage of a lifetime in 6-star ultra-luxury on board Scenic Eclipse, The World’s First Discovery Yachts
Ultra-Luxury Ocean Voyages – Verandah Suite Sale on selected 2024 and 2025 sailings - call now for details
Fly Cruise From
Was £34395pp
Now: £33019
pp
REF: SCENICOSA3280225-2
Antarctica, South Georgia & Falkland Islands
Buenos Aires | Buenos Aires | Ushuaia | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | South Georgia Island | South Georgia Island | South Georgia Island | South Georgia Island | Falkland Islands | More...
28 Feb 2025
22 Nights
Atlantic Islands

Experience the voyage of a lifetime in 6-star ultra-luxury on board Scenic Eclipse, The World’s First Discovery Yachts
Ultra-Luxury Ocean Voyages – Verandah Suite Sale on selected 2024 and 2025 sailings - call now for details
Fly Cruise From
Was £18970pp
Now: £18211
pp
REF: SCENIC311S280225-2
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | El Barranco, Genovesa Island, Galápagos | Darwin Bay, Genovesa Island, Galápagos | Sullivan Bay, Santiago Island, Galápagos | North Seymour Island, Galapagos | Punta Moreno, Isabella Island, Galapagos | Mangle Point, Fernandina Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Cerro Brujo, San Cristóbal Island, Galápagos | San Cristóbal Island, Galápagos | More...
01 Mar 2025
7 Nights
Pacific

Save £2400 per couple
Fly Cruise From
Was £12600pp
Now: £11371
pp
REF: SILVEROR250301007
San Cristóbal, Galapagos to San Cristóbal, Galapagos
San Cristóbal Island, Galápagos | Roca León Dormido | El Barranco, Genovesa Island, Galápagos | Darwin Bay, Genovesa Island, Galápagos | Sullivan Bay, Santiago Island, Galápagos | North Seymour Island, Galapagos | Punta Moreno, Isabella Island, Galapagos | Mangle Point, Fernandina Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Cerro Brujo, San Cristóbal Island, Galápagos | San Cristóbal Island, Galápagos | More...
01 Mar 2025
14 Nights
South America

Save £2400 per couple
Fly Cruise From
Was £22500pp
Now: £20306
pp
REF: SILVEROR250301C14
7 Night Galapagos Inner Loop Cruise
Baltra Island, Galápagos | Rabida Island | Puerto Egas | Elizabeth Bay, Isabela Island, Galápagos | Tagus Cove, Isabella Island, Galapagos | Bartolome Island | Sullivan Bay, Santiago Island, Galápagos | Daphne Major, Galapagos | North Seymour Island, Galapagos | Las Bachas, Santa Cruz Island, Galápagos | Punta Pitt, San Cristóbal Island, Galápagos | Puerto Baquerizo Moreno, San Cristobal Island, Galapagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
02 Mar 2025
7 Nights
Pacific

Cruise Only From
Was £12409pp
Now: £10536
pp
REF: CELEBFL07G055-020325
Rio de Janeiro to Bridgetown
Rio de Janeiro | Rio de Janeiro | Salvador de Bahia | Fortaleza | Santarém | Boca de Valeria | Manaus | Manaus | Manaus | Parintins | Ile Royale, Salvation Islands | Bridgetown
03 Mar 2025
20 Nights
South America

$200 FREE to spend on-board - ONLY when booking with SixStarCruises
Save £2400 per couple
Fly Cruise From
Was £13700pp
Now: £12364
pp
REF: SILVERRA250303020
Rio de Janeiro to Fort Lauderdale, Florida
Rio de Janeiro | Rio de Janeiro | Salvador de Bahia | Fortaleza | Macapa | Santarém | Boca de Valeria | Manaus | Manaus | Manaus | Parintins | Macapa | Ile Royale, Salvation Islands | Bridgetown | More...
03 Mar 2025
29 Nights
South America

Save £2400 per couple
Fly Cruise From
Was £14700pp
Now: £13266
pp
REF: SILVERRA250303C29
Buoyant Rhythms
Buenos Aires | Montevideo | Montevideo | Punta del Este | Balneário de Camboriú | Santos | Ilha Grande | Buzios | Rio de Janeiro | Rio de Janeiro
03 Mar 2025
10 Nights
South America

Ultimate All-Inclusive Cruise Fare now includes: Round-trip Economy flights, transfers between airport and ship PLUS Private Executive Chauffeur Credit*
Fly Cruise From
Was £8049pp
Now: £7264
pp
REF: REGENTSPL250303
Rhythm, Culture & Canary Islands
Buenos Aires | Montevideo | Montevideo | Punta del Este | Balneário de Camboriú | Santos | Ilha Grande | Buzios | Rio de Janeiro | Rio de Janeiro | Buzios | Salvador de Bahia | Maceió | Recife | More...
03 Mar 2025
26 Nights
Atlantic Islands

Ultimate All-Inclusive Cruise Fare now includes: Round-trip Economy flights, transfers between airport and ship PLUS Private Executive Chauffeur Credit*
Fly Cruise From
Was £15389pp
Now: £13888
pp
REF: REGENTSPL250303A

Explore South America on a Finest Collection voyage

Our Finest Collection cruise packages in South America offer tailor-made adventures exclusively for you. Your cruise is paired with a set of immersive land tours dedicated to helping you get right to the heart of the ports on your itinerary. What's more, after days spent hiking across glaciers or exploring iconic cities accompanied by a local tour guide, you can retire to a five-star hotel for a gourmet dinner and spot of well-earned relaxation. 

South America expedition cruises

If you want your South America cruise adventure to be even more unforgettable, embark on an expedition cruise and feel like a true explorer. Sailing to destinations like mysterious Easter Island, wild and rugged Chile, and the positively prehistoric Galapagos islands; once-in-a-lifetime experiences are guaranteed. Accompanied by a dedicated group of expedition experts - from marine biologists to professional adventurers - you willl live like an intrepid explorer and witness natural wonders most people can only dream of.

Book South America cruises with our Cruise Concierge team

If you would like to embark on an adventure you will never forget, call our Cruise Concierge team to book one of the itineraries below. And if you can't find exactly what you are looking for? Call us to build a completely bespoke cruise in South America that incorporates every port and experience you have been dreaming of.

Our Award Winning Service


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